Odorant recognition in insect olfactory system to control insect behaviour

昆虫嗅觉系统中的气味识别以控制昆虫行为

• 批准号: DE160100382
• 负责人: Dr Wei Xu
• 金额: $ 26.06万
• 依托单位: Murdoch University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE160100382
• 关键词: Odorant; recognition; insect; olfactory; system

This project seeks to develop new insights into insect’s ability to detect odour and to identify potential attractant compounds to support the development of environmentally safer insect pest control strategies. Insect reliance on senses to detect food has considerable potential for the development of odour-based behaviour control methods. Odorant binding proteins (OBPs) are an ideal molecular target to identify odorant-based insect attractants from a large pool of compounds. However, our understanding of the molecular mechanism that mediates chemoreception in insects is limited. This project may provide valuable insight into the role of OBPs in molecular recognition in insects and develop a new way to screen attractants based on the binding ability of OBPs to compounds.

该项目旨在发展对昆虫嗅觉能力的新见解，并确定潜在的引诱剂化合物，以支持开发环境更安全的虫害控制战略。昆虫依靠感官来检测食物，在开发基于气味的行为控制方法方面具有相当大的潜力。气味结合蛋白(OBP)是从大量化合物中识别气味类昆虫引诱剂的理想分子靶标。然而，我们对昆虫化学感受的分子机制的了解是有限的。该项目可能为了解OBPs在昆虫分子识别中的作用提供有价值的见解，并开发一种基于OBPs与化合物的结合能力来筛选引诱剂的新方法。