光化学反応によるエナメル質の再石灰化に及ぼす液組成の検討

通过光化学反应检查液体成分对牙釉质再矿化的影响

• 批准号: 08771980
• 负责人: 国分 美和子
• 金额: $ 0.58万
• 依托单位: Ohu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Encouragement of Young Scientists (A)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-08771980/
• 关键词: エナメル質; エキシマレーザー光照射; 再石灰化; 光化学反応

人工的に脱灰したエナメル質片にエキシマレーザー光照射を行い、再石灰化液組成による再石灰化反応の促進と応用領域の拡大について基礎的検討を加えた。エナメル質片は、ヒト上顎中切歯の唇面をエポキシ樹脂で包埋して、エナメル質表層を研磨除去して作製した。人工脱灰を行った後、再石灰化液作用とレーザー光照射後、人工唾液に浸漬した群(同時作用+人工唾液),再石灰化液作用とレーザー光照射した群(同時作用)、人工唾液にのみ浸漬した群(人工唾液)、非照射・無処理群(対照)の4群に分け、SEM像の観察、VHNおよびCa溶出量(耐酸性試験)の比較を行った。KrF(248nm)エキシマレーザー光の照射条件は,70mJ/cm^2,2000shotsとした。再石灰化液の組成は,Ca:0.3〜0.5mM,P:1.8〜5.3mM,F:0〜5.2mM,NaHCO_3:0〜20mM,CMC:0〜1%の間で種々の条件を設定した。人工唾液組成は0.5%-CMC,1.5mM-CaCl_2・2H_2O,0.9mM-K_2HPO_4,0.02ppm-NaF,pH7.0とし、37℃、48時間浸漬を行った。再石灰化液の組成がCa:3.0mM,P:1.8mM,F:0.6mM,NaHCO_3:20mM,CMC:1%と、Ca:3.0mM,P:1.8mM,F:5.2mM,NaHCO_3:1mM,CMC:1%の同時作用および同時作用+人工唾液のエナメル質片のSEM像からは,再石灰化反応によると考えられる堆積物が観察された。また、硬度は対照<人工唾液<同時作用<同時作用+人工唾液の順で、両再石灰化液とも群間に有意差が認められた。耐酸性試験では、Ca溶出量が同時作用<同時作用+人工唾液<人工唾液<対照の順で、両再石灰化液とも群間に有意差が認められた。硬度の回復と耐酸性試験の結果は、一致した傾向を示さなかったが、両石灰化液とエキシマレーザー光照射の同時作用が硬度の回復や耐酸性の付与に大きく寄与することが示唆された。

The artificial de-ash system is used to remove ash. The film is used to illuminate the light, and then the liming solution is composed to promote the use of large-scale chemical materials in the field. Cut your lips in the middle, cut your lips in the middle, cover your lips with grease, and grind them to remove them. After artificial deashing, liming liquid action, artificial saliva immersion (simultaneous action + artificial saliva). The effects of calcinated solution on light irradiation (simultaneous action), artificial saliva immersion (artificial saliva), non-irradiation (artificial saliva), SEM image analysis, VHN Ca dissolution (acid tolerance) were compared. KrF (248nm) radiation conditions, 70mJ/ cm ^ 2, 2000shots radiation conditions. Then the liming solution is composed, and the conditions of Ca:0.3~0.5mM,P:1.8~5.3mM,F:0~5.2mM,NaHCO_3:0~20mM,CMC:0~1% are set. Artificial saliva is composed of 0.5%-CMC,1.5mM-CaCl_ 2 ·2H _ 2O 0.9mm color Kappa 2HPOY 4 0.02ppm NAF journal pH 7.0 ℃, 37 ℃, 48 time immersion time. Then the liming solution was composed of Ca:3.0mM,P:1.8mM,F:0.6mM,NaHCO_3:20mM,CMC:1% and Ca:3.0mM,P:1.8mM,F:5.2mM,NaHCO_3:1mM,CMC:1% simultaneously and artificial saliva was used to detect the SEM image, and then the liming reaction was used to examine the stack active material. The simultaneous action of lt; artificial saliva and lt; and the simultaneous action of lt; + artificial saliva and re-calcareous fluid were intentionally different from each other. The simultaneous effect of acid-resistant salt and Ca dissolution dose-lt; + artificial saliva-lt; artificial saliva-lt; radiation and liming solution were intentionally different from each other. The results of hardness test, acid resistance test, consistent temperature test and calcinating liquid temperature test show that the hardness test results show that the acid resistance test results show that the hardness test results show that the hardness test results show that the acid resistance test results show that the hardness test results show that the hardness test results show that the acid resistance test results, the consistent test results show that the hardness test results show that the acid resistance test results, the consistent test results show that the hardness test results, the consistent test results show that the hardness test results, the consistent test results show that the hardness test results, the consistent test results show that the hardness test results, the consistent test results show that the hardness test results, the consistent test results, the calcareous solution temperature temperature test light irradiation at the same time, the hardness test results show that the acid resistance test results show that the hardness test results show that the hardness test results show that the acid resistance test results, the consistent test results

项目成果

秋山哲夫,宮澤忠蔵,国分美和子 他3名: "再石灰化液のエナメル質作用時におけるエキシマレーザー光照射の影響" 口腔衛生学会雑誌. 46・4. 512-513 (1996)

Tetsuo Akiyama、Chuzo Miyazawa、Miwako Kokubun 等 3 人：“准分子激光照射对牙釉质再矿化液作用的影响”口腔卫生学会杂志 46・4（1996 年）。