Genetics of Postmenopausal Bone Loss

绝经后骨质流失的遗传学

• 批准号: LP0669653
• 负责人: Prof Philip Sambrook
• 金额: $ 6.26万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-11-23 至 2008-11-21
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0669653
• 关键词: Genetics; Postmenopausal; Bone; Loss

The major consequence of bone loss in our ageing society is fracture. At 50 years for women, the lifetime risk of sustaining an osteoporotic fracture is 50%. The consequences of these fractures, which can include reduced life expectancy, prolonged medical care, and loss of independence, have a profound socioeconomic impact in an ageing population. The proposed study offers a unique opportunity to examine the contribution of genetic factors to postmenopausal osteoporosis.

在我们的老龄化社会中，骨质流失的主要后果是骨折。 对于50岁的女性来说，维持骨质疏松性骨折的终生风险为50%。这些骨折的后果可能包括预期寿命缩短、医疗护理延长和丧失独立性，对老龄化人口产生深远的社会经济影响。这项研究提供了一个独特的机会来研究遗传因素对绝经后骨质疏松症的影响。