Small RNA transport from pathogens to plants (B14*)

了解病原体克服植物对寄主免疫的分子原理是制定新的植物保护策略的必要条件。真菌和卵菌病原体通过跨界RNA干扰将小RNA传递到宿主植物中以沉默植物免疫，这是宿主-微生物相互作用中的一个新兴概念。本项目旨在阐明sRNA从病原体转运到植物的分子机制和功能。我们假设病原体sRNAs的传递是通过细胞外囊泡发生的。确定跨界sRNA通信的潜在机制和功能将有助于开发作物保护的新应用。

Understanding the molecular principles by which pathogens overcome plant immunity to parasite hosts is mandatory to develop novel plant protection strategies. Fungal and oomycete pathogens deliver small RNAs into host plants to silence plant immunity via cross-kingdom RNA interference, an emerging concept in host-microbe interaction. This project aims at elucidating the molecular mechanisms and functions of sRNA transport from pathogens into plants. We hypothesize that delivery of pathogen sRNAs occurs via extracellular vesicles. Identifying the underlying mechanisms and functions in cross-kingdom sRNA communication will help to develop new applications for crop protection.