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Basic Research on Identifing Location and Temperature of Cancer using the Measurement of Human Body Surface Impedance

利用人体表面阻抗测量识别癌症位置和温度的基础研究

基本信息

批准号：
01480272
负责人：
IKEDA Tetsuo
金额：
$ 4.48万
依托单位：
Nagoya Institute of Technology
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1989
资助国家：
日本
起止时间：
1989 至 1991
项目状态：
已结题

项目摘要

Usually performing operations and/or using chemical medicines are popular for remedying cancers. Recently hyperthermia methods are utilized in many cases. This method makes use of the effect that cancer cells die out for the temperature above 42 ﾟC. Its characteristics exists in non-stimulating property. However, the problems of identifying the location of the cancer and measuring the temperature of it are not solved yet. It is considered that cancer cells have different dielectric constants and conductivities from those of ordinary cells. So, by measuring these constants, it is possible to know the temperature of the cancer. These are the main purposes of this research.In 1989, we made the fundamental experiments for measuring the reflection coefficient of the experimental materials using the coaxial type applicator having 50 OMEGA characteristic impedance and obtained the dielectric constants and the conductivities of the. materials. We also made clear the practical problems in this … More experiment. In 1990, we made three kinds of new applicators and measured the dielectric constant and the conductivity more carefully and exactly. We also built up the computer system to measure these quantities automatically. In 1991 and 1992, we continued the same experiments, however, we examined the dielectric constant and the conductivity over the frequency range from 50 to 550 MHz. As the experimental materials, we had used salty water, roast ham and human body. Next, not measuring the reflection coefficient S_<11>, but we measured the transmitting coefficient S_<21>. Measuring the coefficient S_<2l> leads to the impedance CT with the scanning method. Using this result, we also examined the temperature dependency of the dielectric constant and the conductivity and confirmed their large dependency on it. This result shows the future possibility of measuring the temperature of the cancer in the human body using the technology of the impedance CT.Through 1989 to 1992, we had measured dielectric constants and conductivities of various biological experimental materials as well as the temperature dependency of them. We had obtained the basic data for identifying the location and the temperature of the cancer in the human body. Less

通常，进行手术和/或使用化学药物是治疗癌症的流行方法。最近热疗方法被用于许多情况。这种方法利用了癌细胞在42摄氏度以上的温度下死亡的效果。其特点是无刺激性。然而，识别癌症位置和测量癌症温度的问题尚未解决。认为癌细胞具有与普通细胞不同的介电常数和电导率。因此，通过测量这些常数，可以知道癌症的温度。1989年，我们用特性阻抗为50 Ω的同轴型辐射器进行了测量实验材料反射系数的基础实验，得到了材料的介电常数和电导率。材料.我们也明确了这方面的实际问题 ...更多信息实验1990年，我们研制了三种新的施加器，并对介电常数和电导率进行了更仔细、更准确的测量。我们还建立了计算机系统来自动测量这些量。在1991年和1992年，我们继续相同的实验，但是，我们检查了介电常数和电导率的频率范围从50到550兆赫。作为实验材料，我们使用了盐水、烤火腿和人体。接下来，不测量反射系数S_<11>，而是测量透射系数S_<21>。通过测量阻抗系数S_1<2l>，得到了阻抗CT的扫描方法。利用这一结果，我们还检查了介电常数和电导率的温度依赖性，并确认它们对温度的依赖性很大。这一结果表明，未来可能使用阻抗CT技术测量人体内癌症的温度。我们测量了各种生物实验材料的介电常数和电导率以及它们的温度依赖性。我们已经获得了确定人体癌症位置和温度的基础数据。少