Basic Research on Identifing Location and Temperature of Cancer using the Measurement of Human Body Surface Impedance

通常情况下，手术和/或使用化学药物是治疗癌症的流行方法。近年来，热疗方法在许多病例中得到应用。该方法利用了癌细胞在42ﾟC以上温度下死亡的效应，其特点是无刺激性。然而，识别癌症的位置和测量其温度的问题还没有解决。人们认为癌细胞具有不同于普通细胞的介电常数和电导率。因此，通过测量这些常数，就有可能知道癌症的温度。1989年，我们用特性阻抗为50欧米伽的同轴式敷贴器进行了测量实验材料反射系数的基础实验，得到了材料的介电常数和电导率。材料。我们还明确了…中的实际问题更多的实验。1990年，我们研制了三种新的涂布器，并对其介电常数和电导率进行了更细致、更准确的测量。我们还建立了计算机系统来自动测量这些数量。在1991年和1992年，我们继续进行同样的实验，但是，我们在50到550 MHz的频率范围内测试了介电常数和电导率。以咸水、烤火腿和人体为实验材料。接下来，我们测量的不是反射系数S，而是透射率S。通过对S系数的测量，得到了扫描法阻抗CT。利用这一结果，我们还考察了介电常数和电导率的温度依赖关系，并证实了它们对温度的依赖关系。这一结果表明了利用阻抗CT技术测量人体内癌症温度的未来可能性。从1989到1992年，我们测量了各种生物实验材料的介电常数和电导率，以及它们的温度依赖关系。我们已经获得了确定癌症在人体内的位置和温度的基本数据。较少

Usually performing operations and/or using chemical medicines are popular for remedying cancers. Recently hyperthermia methods are utilized in many cases. This method makes use of the effect that cancer cells die out for the temperature above 42 ﾟC. Its characteristics exists in non-stimulating property. However, the problems of identifying the location of the cancer and measuring the temperature of it are not solved yet. It is considered that cancer cells have different dielectric constants and conductivities from those of ordinary cells. So, by measuring these constants, it is possible to know the temperature of the cancer. These are the main purposes of this research.In 1989, we made the fundamental experiments for measuring the reflection coefficient of the experimental materials using the coaxial type applicator having 50 OMEGA characteristic impedance and obtained the dielectric constants and the conductivities of the. materials. We also made clear the practical problems in this … More experiment. In 1990, we made three kinds of new applicators and measured the dielectric constant and the conductivity more carefully and exactly. We also built up the computer system to measure these quantities automatically. In 1991 and 1992, we continued the same experiments, however, we examined the dielectric constant and the conductivity over the frequency range from 50 to 550 MHz. As the experimental materials, we had used salty water, roast ham and human body. Next, not measuring the reflection coefficient S_<11>, but we measured the transmitting coefficient S_<21>. Measuring the coefficient S_<2l> leads to the impedance CT with the scanning method. Using this result, we also examined the temperature dependency of the dielectric constant and the conductivity and confirmed their large dependency on it. This result shows the future possibility of measuring the temperature of the cancer in the human body using the technology of the impedance CT.Through 1989 to 1992, we had measured dielectric constants and conductivities of various biological experimental materials as well as the temperature dependency of them. We had obtained the basic data for identifying the location and the temperature of the cancer in the human body. Less