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Self Organization into Bilayer of Fluorocarbon Amphiphiles in Aromatic and Aliphatic Solvent

芳香族和脂肪族溶剂中氟碳两亲物自组织成双层

基本信息

批准号：
02453109
负责人：
KUNITAKE Toyoki
金额：
$ 3.26万
依托单位：
Kyushu University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1990
资助国家：
日本
起止时间：
1990 至 1991
项目状态：
已结题

项目摘要

In this project, we extended the concept of self-organizing bilayer formation from aqueous systems to non-aqueous systems, and established the molecular design of the component amphiphile. Novel amphiphilic compounds which contain two fluorocarbon chains as solvophobic unit and flexible oleyl chain as solvophilic unit underwent self-organization in hydrocarbon meflia to bilayer assemblies similar to those in aqueous media. Electron microscopy displayed their varied morphologies. These amphiphiles commonly contained the amide connector that promoted intermolecular attraction. Infrared spectroscopy showed that the amide bond shifted to a shorter wavenumbers in chlorocyclohexane in which the bilayer was formed. This shift was lost above the phase transition temperature as determined by differentialscanning calorimetry (DSC). The IR data also showed that the fluorocarbon chain assumed a helical conformation at 15ﾟC and a zig-zag conformation at 40ﾟC. This conformational change was associated with the bilayer formation. The monolayer formation was observed at the air-chlorocyplohexane interface. The molecular cross-section agreed with that of the fluorocarbon chain, indicating the presence of a condensed monolayer. The thermodynamic changes of the surface adsorption agreed with those obtained for the dispersed bilayer by DSC. Therefore, the phase transition of the dispersed bilayer must occur between the monomeric dispersion and the bilayer, unlike those of aqueous bilayers. In conclusion, molecular design of non-aqueous bilayers needs to be based on long fluorocarbon chains, effective intermolecular interactions such as hydrogen bonding and dipolar attraction, and enhanced solvophilicity.

本研究将自组织双层形成的概念从水相体系扩展到非水相体系，并建立了两亲分子的分子设计。新型两亲化合物含有两个氟碳链作为疏溶剂单元和柔性油烯基链作为亲溶剂单元，在烃类介质中自组装成类似于在水介质中的双层组装体。电子显微镜显示其形态各异。这些两亲物通常含有促进分子间吸引的酰胺连接体。红外光谱表明，在氯代环己烷中酰胺键向较短波数方向移动，形成了双分子层。通过差示扫描量热法（DSC）测定，在高于相变温度时，这种位移消失。红外光谱数据还表明，碳氟链在15 ℃时呈现螺旋构象，在40 ℃时呈现锯齿构象。这种构象变化与双分子层的形成有关。在空气-氯环己烷界面处观察到单层形成。的分子横截面同意的氟碳链，表明存在一个凝聚的单层。表面吸附的热力学变化与DSC所获得的分散双层的热力学变化一致。因此，分散双层的相变必须发生在单体分散体和双层之间，不同于水性双层。总之，非水双层膜的分子设计需要基于长的氟碳链、有效的分子间相互作用如氢键和偶极吸引力以及增强的亲溶剂性。