A long term follow-up study of first-break schizophrenics : Outcome and social, psychological and biological factors

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The findings obtained in this long term follow-up research on the relation between outcome of first-break schizophrenics and social, psychological and biological factors are as follows;(1) Five subjects were dead during 10 years after first contact with psychiatric facility and the rate of death in all subjects was 4.7%.(2) Occupation: Forty-three percent of original subjects was employed, self-employed or housewife.(3) Marital state: The percentage of those got married was 23%. Male subjects had lower marriage rate and higher divorce rate than female subjects.(4) Economical level: Higher than average class decreased at the time of 10-year follow-up in comparison with the time of first contact.(5) Social outcome and heredity: No significant difference was found in mental disorders of biological parents between good and poor outcome group, however major psychoses such as schizophrenia or depression were found only in the latter group.(6) CATEGO class of PSE-9: There were more cases with class S in good outcome group without statistical significance.(7) Social outcome and history of maladjustment in childhood and/or in adolescence: More positive ratings of maladjustment in poor outcome group than in good outcome group.(8) Clinical course: The most frequent type of course was those with psychotic relapses with incomplete remission between relapses.