Design and manufacturing of graded high-purity magnesium-calcium-zinc-material by fractional crystallization for the application as biodegradable implant material

分级结晶高纯镁钙锌材料的设计和制造，用于生物可降解植入材料

• 批准号: 431892627
• 负责人: Professor Dr.-Ing. Bernd Friedrich
• 金额: --
• 依托单位: Institut für Materialphysik im Weltraum
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2019
• 资助国家: 德国
• 起止时间: 2018-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/431892627?language=en
• 关键词: Design; manufacturing; graded; purity; magnesium

The objective of this research project is to develop an innovativealternative manufacturing process to vacuum distillation in order tomanufacture high-purity magnesium for implementation asbiodegradable implant material. As this proposed method is based on fractional crystallization, this production method of high-purity magnesium and magnesium alloys will reduce equipment Investments while simultaneously increasing production speed and resource efficiency. Utilizing the “striation” phenomena, alloying elements (e.g. calcium and zinc) will be integrated into the substrate material with increasing concentrations over the cross-section, but within one processing step and without the currently required re-melting step. With the production of graded magnesium materials, the currently unattainable degradation design defined in the literature as optimally initiating slowly before increasing degradation rate, can be realized. Investigations regarding the degradation processes will confirm the suitability of fractional crystallization with regards to the manufacturing aspects in addition to the targeted degradation design while simultaneously characterizing the corrosion mechanisms which occur in graded materials. In order to accomplish this, high-purity magnesium is required as impurities are known to cause synergistic effects with both the microstructure and corrosion processes. Through this project, an essential, fundamentally-based contribution to the manufacturing and development of implantable magnesium can be achieved.

该研究项目的目标是开发一种真空蒸馏的创新替代制造工艺，以制造用作可生物降解植入材料的高纯度镁。由于该方法基于分步结晶，因此这种高纯镁和镁合金的生产方法将减少设备投资，同时提高生产速度和资源效率。利用“条纹”现象，合金元素（例如钙和锌）将以在横截面上增加的浓度整合到基底材料中，但是在一个处理步骤内并且没有当前所需的再熔化步骤。随着梯度镁材料的生产，目前无法实现的降解设计，在文献中定义为最佳的缓慢开始之前，提高降解速率，可以实现。关于降解过程的研究将证实除了目标降解设计外，分步结晶在生产方面的适用性，同时表征分级材料中发生的腐蚀机制。为了实现这一点，需要高纯度的镁，因为已知杂质会引起与微观结构和腐蚀过程的协同效应。通过该项目，可以实现对植入式镁的制造和开发的重要的、基于基础的贡献。