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Three-dimensional ultrastructural study on fibril arrangement of jawbone matrix and articular disk

颌骨基质和关节盘原纤维排列的三维超微结构研究

基本信息

批准号：
05670027
负责人：
TAKIGUCHI Reiji
金额：
$ 1.28万
依托单位：
Showa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1993
资助国家：
日本
起止时间：
1993 至 1994
项目状态：
已结题

项目摘要

On the purpose to clarify the relationship between fibril arrangement of bone matrix and stress or structural changes of aging, we examined the matrix surface of jaw bones and the articular disks with scanning electron microscope.The surface of mandibles of mature crab-eating monkeys was composed of collagen fibril bundles. At the mandibular body, main collagen finbril bundles were running in parallel along the long axis of mandibular body. At the uneven surface of mandibular body, bundles mingled each other. Bundles were running in parallel along the alveolar border. However, bundles were running perpen-dicularly at the surface of alveolar bone. It was suggested that the arrangement of collagen fibril bundles of alveolar bone was related to the direction of the masticatory strength. At the surface of ramus of mandible, bundles were running along the long axis of ramus of mandible.The fibrous zone of the mandibular condyle from rat fetuses was poor in intercellular matrix. In 1-week-old rats, the fibrils were orderly rearranged and closely packed except fibrillar network in the superficial layr of the condyle. At 8 weeks, three dimensionally interwoven bundles of fibrils were present and the fibrillar network was less prominent. In mature and senile rats, the fibrillar bundles of the articular surface increased in number and width indicative of a well-development.The disk surfaces of immature rats were occupied by collagen fibrils interwoven in the form of network. The fibril network in matured and aged rats was not a conspicuous as in immature rat : in those rats, fibril bundles oriented principally in an anteroposterior direction and parallel to the articular surfaces were predominantly present in the surfaces, while the fibril network was arranged more roughly than in immature rats. This is similar in appearance to that seen on the mandibular condylar surface.

为了阐明骨基质纤维排列与衰老应力或结构变化的关系，用扫描电子显微镜观察了成年食蟹猴下颌骨基质表面和关节盘表面的胶原纤维束。在下颌体部，主胶原纤维束沿下颌体长轴平行排列。在下颌骨体凹凸不平的表面，骨束相互交织。小束沿肺泡边缘平行排列。而牙槽骨表面呈束状排列。提示牙槽骨胶原纤维束的排列与咀嚼强度的方向有关。在下颌支表面，成束沿下颌支长轴排列，胎鼠下颌骨髁状突纤维带细胞间基质稀少。1周龄大鼠关节突除浅层有纤维网状结构外，其余纤维排列整齐、紧密堆积。在8周时，出现三维交织的纤维束，纤维网络不那么突出。成年组和老年组大鼠关节面纤维束数量增多、宽度增大，提示关节盘发育良好，幼年组关节盘面被胶原纤维以网络状相互交织占据。成熟和老年大鼠的纤维网络不如未成熟大鼠明显：这些大鼠的表面主要存在以前后方向为主的平行于关节表面的纤维束，而纤维网络的排列比未成熟大鼠更粗糙。这在外观上类似于在下颌骨髁状突表面上看到的。