Study on the evaluation of risk factors for asthma-like symptom of three year old children

三岁儿童哮喘样症状危险因素评价研究

• 批准号: 05670327
• 负责人: KAGAWA Jun
• 金额: $ 1.15万
• 依托单位: Tokyo Women's Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05670327/
• 关键词: Three year-old children; Athma-like symptom; Epidemiology; Environmental factors; Passive smoking; Urinary cotinine; Nitrogen dioxide personal exposure; 3歳児健康診査; 窒素酸化物; 個人暴露; 3歳児検診; 喘息様症状; 質問票

Study on the evaluation of risk factors for asthma-like symptom of three year old children.In order to study the risk factors for asthma-like symptom, the relationship was examined between allergic disposition, infantile nurtrition, smoking with family, dwelling condition and heating apparatus and the prevalence rate of asthma-like symptom in 790 three year old children who, for health chick up, visited the urban public health center located in Tokyo, in 1993-1994. The results were as follows ;1. The study established a prevalence rate of 9.9% in boys and 6.7% in girls with an overall average of 8.3%, which was higher than that of other stydies in children.2. Medical anamnesis of allergic disease except bronchial asthma, family history of allergy and infection of lower bronchus all were found influential to prevalence of asthma-like symptom.3. We analyzed urinary continine as a biochemical marker of passive smoking. The urinary continine detection rate (44.7%) of children who lived with smokers was higher than that (8.0%)of children who did not.4. One hundred and two children were requested to put on NO exposure levels were recorded by some children. It's thought the reason is the children were exposed to high NO at homes, due to the use of winter heating apparatus. But the use of various type heating apparatus was not related significantly to the prevalence rate of asthma-like symptom.

3岁儿童哮喘样症状危险因素的评价为探讨3岁儿童哮喘样症状的危险因素，对790名3岁健康儿童进行了过敏性、婴幼儿养育、家庭吸烟、居住条件、取暖设备等与哮喘样症状患病率的关系研究，1993-1994年访问了位于东京的城市公共卫生中心。结果如下：1.本研究确定的患病率为9.9%的男孩和6.7%的女孩，总平均为8.3%，这是高于其他研究的儿童。除支气管哮喘外，其他过敏性疾病病史、过敏家族史、下支气管感染均对哮喘样哮喘的患病率有影响.我们分析了尿continine作为被动吸烟的生化标志物。与吸烟者共同生活的儿童尿Continine检出率（44.7%）高于不吸烟者（8.0%）. 102名儿童被要求穿上NO暴露水平被一些儿童记录。据认为，原因是儿童在家中暴露于高NO，由于使用冬季取暖设备。不同类型取暖器具的使用与哮喘样症状的发生率无显著相关性。