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Study on Mass Health Examination of Osteoporosis

骨质疏松症大众健康检查研究

基本信息

批准号：
06454244
负责人：
TSUNODA Humio
金额：
$ 3.97万
依托单位：
Iwate Medical University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1995
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06454244/
关键词：
Bone Mineral Measurements Osteoporosis Mass Examination Standard Value of Bone Mineral Density Adult Women Dual Energy X-ray Absorptiometry Ultrasound Bone Densitometry

项目摘要

The aim of this study was to establish the efficient and accurate method for mass-screening of osteoporosis. Norland XR-26 as the Dual Energy X-ray Absorptiometry (DEXA) system had excellent accuracy and precision, but the time required for the anterior-posterior spine measurement by this system was too long to measure the enough number of candidate for health examination. We modified this system, and required time was 30% shorten. With this method, it is possible to make 50 to 60 Bone Mineral Density (BMD) measurements per day. Furthermore we researched another method, and selected the ultrasound bone densitometry (US) as a suitable substitute method for mass examination. About 1300 female examinees were measured by Lunar A-1000 US system. With this method 70 examinees could measured per day. From the bone stiffness of the calcaneus in an ultrasound method, it is difficult to come to accurate grip with the systemic bone volume, but this method makes up for the disadvantages of DEXA and is of use for screenings. So that we recommend a mass screening system for osteoporosis in which the ultrasound method is made the primary examination and DEXA is made the secondary one. From the Mass examination by this system we found the knowledge about the relationship between BMD or bone stiffness and life style, for example that the exercise habit in young age were attribute to the good condition of bone.

本研究旨在建立一种高效、准确的骨质疏松症普查方法。Norland XR-26双能X线吸收测量仪（DEXA）具有良好的准确性和精密度，但该系统测量脊柱前后位所需时间过长，无法测量足够数量的健康检查对象。我们对该系统进行了改进，所需时间缩短了30%。使用这种方法，每天可以进行50至60次骨矿物质密度（BMD）测量。并对另一种检查方法进行了研究，选择超声骨密度测定（US）作为适合的替代检查方法。采用Lunar A-1000 US系统对约1300名女性受试者进行了测量。该方法每天可测70名受检者。从跟骨的骨硬度在超声方法中，它是很难来与全身骨体积的准确把握，但这种方法弥补了DEXA的缺点，是用于筛选。因此，我们推荐一种以超声检查为主，DEXA检查为辅的骨质疏松症普查系统。通过该系统进行的大量检测，我们发现了生活方式与骨密度或骨硬度之间的关系，如年轻时的运动习惯与良好的骨状况有关。