The comparative study of MR functional imaging and H_2^<15>O-PET

本研究的目的是探讨磁共振功能成像(FMRI)能否评价刺激的两个初级NAD相关皮质区，并通过与已建立的H_2和15&GT；O-PET脑功能检查相比较，阐明这一激活皮质区的意义。基础研究表明，利用计算机图形学视频的视觉刺激适合于激活大脑皮质的大面积，EPI方法适合作为fMRI的脉冲序列，用于三维评价激活的皮质区域。受试者为9名成人，分别在fMRI和H_2^&t；15&gt；O-PET中接受相同的视觉刺激。两项研究均在2周内完成。两项研究的图像对比显示：1，fMRI不仅激活了初级视觉皮质，还激活了视觉关联皮质。O-PET。3的激活视觉关联区的比较表明，后者通常比前者大。1，2揭示了fMRI可以检测到与H_2^&lt；15；O-PET几乎相同的激活的视觉皮质区域。在3上看到的激活的视皮层的差异可能对应于参与颜色知觉的第四个视区。

The purpose of this research project is whether MR functional imaging (fMRI) can evaluate both primary nad association cortical areas of the stimulation, and can clarify the significance of this activated cortical area by comparing with established brain functional examination of H_2^<15>O-PET.Basic study was carrid out in 1994 and the early period of 1995. Basic study showed that the visual stimulation using the video of computer graphics was suitale for activating the large area of cortex, and EPI method was suitable as the pulse sequence of fMRI for evaluating the activated cortical area three dimensionally.The comparative study was carried out in 1995. Subject was 9 adults, each of them had the same visual stimulation during fMRI and H_2^<15>O-PET.Both studies were done within 2 weeks.The comparison of images of both studies revealed below ;1, fMRI activated not only the primary visual cortex but also visual association cortex.2, The extend of activated isual cortices by fMRI was almost the same as that of H_2^<15>O-PET.3, The comparison between the activated visual association areas by monoclonal video and by color video showed that the latter was usually larger than the former.1,2 revealed that fMRI can detect the activated visual cortical areas as almost the same extend as H_2^<15>O-PET.The difference in the activated visual cortex seen on 3 may repressent that this difference corresponds to the fourth visual area which engages in the color perception.