The comparative study of MR functional imaging and H_2^<15>O-PET

MR功能成像与H_2^<15>O-PET的对比研究

• 批准号: 06454322
• 负责人: NISHIKAWA Junichi
• 金额: $ 1.54万
• 依托单位: University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06454322/
• 关键词: MR functional imaging (fMRI); H_2^<15>O-PET; Visual stimulation; Visual association area; MR functional imaging (fMRI); 聴覚刺激; 手指運動刺激

The purpose of this research project is whether MR functional imaging (fMRI) can evaluate both primary nad association cortical areas of the stimulation, and can clarify the significance of this activated cortical area by comparing with established brain functional examination of H_2^<15>O-PET.Basic study was carrid out in 1994 and the early period of 1995. Basic study showed that the visual stimulation using the video of computer graphics was suitale for activating the large area of cortex, and EPI method was suitable as the pulse sequence of fMRI for evaluating the activated cortical area three dimensionally.The comparative study was carried out in 1995. Subject was 9 adults, each of them had the same visual stimulation during fMRI and H_2^<15>O-PET.Both studies were done within 2 weeks.The comparison of images of both studies revealed below ;1, fMRI activated not only the primary visual cortex but also visual association cortex.2, The extend of activated isual cortices by fMRI was almost the same as that of H_2^<15>O-PET.3, The comparison between the activated visual association areas by monoclonal video and by color video showed that the latter was usually larger than the former.1,2 revealed that fMRI can detect the activated visual cortical areas as almost the same extend as H_2^<15>O-PET.The difference in the activated visual cortex seen on 3 may repressent that this difference corresponds to the fourth visual area which engages in the color perception.

该研究项目的目的是MR功能成像（fMRI）是否可以评估刺激的主要NAD NAD关联皮质区域，并且可以通过与H_2^<15> O-PET的H_2^<15> O-PET. BASIC研究中的较大的研究中的刺激性研究表明，刺激的早期启动的视频是，计算机的视频是在1994年携带的。皮质和EPI方法适合作为FMRI的脉冲序列，用于评估激活的皮质区域三维。比较研究是在1995年进行的。受试者是9个成年人，每个人在fmri和H_2^<15> o-pet.-pet.的研究中都具有相同的视觉刺激。还有视觉关联皮层。2，通过fMRI激活的伊斯基皮质扩展与H_2^<15> o-pet.3，单克隆视频通过彩色视频的激活视觉关联区域之间的比较，后者表明，后者通常比前者更大。1,2揭示了与激活的区域相同的<-fmri <fmri <fmri <fmri <fmri <fmri <fmri <2 3月3日看到的活化视觉皮层可能会压抑，因为这种差异对应于参与颜色感知的第四个视觉区域。