Responses of biogenic amines,cell-mediated immunity and cerebral metabolism in Multiple Organ Failure condition.

血清素和血管紧张素转化酶被量化为急性呼吸道失败的代谢功能。对照组中血清素的吸收率为45.3<plus-minus> 22.3%，与ARF中的-2.6<plus-minus>61.8相比。在两个群体之间没有任何意义。急性呼吸道中的ACE失效较低，对照组中的20.1<加减>10.7，低于30.8<加减>6.0 U/ml。There is significant between two groups（P<0.05）。Angiotensin converting enzyme is good indicator for disturbance of metabolic function of lung in acute respiratory failure with MOF。Decrease of ACE may explain to the extent of functional involvement of the epithelial cell of pulmonary v的MOF with over two organs consumption of complements may be appered but is not firmly admitted。在活着的群体和死去的群体之间没有任何意义。在细胞介导的免疫功能中，T细胞的两个组都是严重被抑制的。In alive group OKT4+，OKT8+ percentage are maintained within normal range。However in dead group those surface antigens below normal range， especially OKT4+ apparantly decreased at stastical significant（p.05）。Ration OKT4+/8+ seemingly show normally. OKT8+ according with the decrease of OKT4+。B cell（OKia1） maintained normally during clinical course both groups。MOF中二级免疫能力的主要原因是T细胞功能的抑制和T细胞的降解。因此，要观察到OKT 4+和OKT 8 + T单元格的影响，这是可能知道MOF的二级免疫度。

Serotonin and Angiotensin converting enzyme were mesured to eclucidate the metabolic function of lung in acute respiratory failure. Absorption rate to lung of Serotonin in comtrol group is 45.3<plus-minus>22.3% compared to -2.6<plus-minus>61.8 in ARF. There is not significant between two groups. ACE in acute respiratory failure is lower ,20.1<plus-minus>10.7, than 30.8<plus-minus>6.0 U/ml in control group. There is significant between two groups(P<0.05). Angiotensin converting enzyme is good indicator for disturbance of metabolic function of lung in acute respiratory failure with MOF. Decrease of ACE may explain to the extent of functional involvement of the epithelial cell of pulmonary vキノウ ハ キョIn MOF with over two organs consumption of complements may be appered but is not firmly admitted. There is not significant between alive group and dead one. In cell-mediated immunity function of T cell is severely inhibited both groups. In alive group OKT4+,OKT8+ percentage are maintained within normal range. However in dead group those surface antigens decreased below normal range, especially OKT4+ apparantly decreased at stastical significant(p .05). Ration OKT4+/8+ seemingly show normally. This normality is due to decrease of OKT8+ according with the decrease of OKT4+. B cell(OKIa1) maintained normally during clinical course both groups. The main causes of secondary immunodeficiency in MOF are the inhibition of T cell function and the decrease nember of T cells. Therefore to observe the influence to OKT4+ and OKT8+ T cell, it is possible to know the degree of secondary immunodeficiency of MOF.