Syntheses and Properties of Symmetrical Cage Compounds, in which All Six, Eight or Ten Lone Pairs on Nitrogen Atoms at Bridgehead or Intervening Pyridine Rings are Oriented toward the Central Cavity.

对称笼型化合物的合成和性质，其中桥头或中间吡啶环上氮原子上的所有六个、八个或十个孤对对都朝向中心空腔。

• 批准号: 61470027
• 负责人: INAZU Takahiko
• 金额: $ 4.16万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1987
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-61470027/
• 关键词: Cryptand; inclusion phenomena; metal complex; macrocyclic polyamine; bridged aromatic compound; ion transfer; 包接化合物; 多環式ポリアミン; イオン選択性

Three dimensional Cryptands, in which all six, eight or ten lone pairs on nitrogen atoms at bridgehead or intervening pyridine rings are oriented toward the central cavity, were synthesized.The compounds, in which of the six benzene rings, four or all six rings are replaced by the pyridine rings, were obtained as their alkali metal cryptates. Complexation ability was enhanced by increasing number of intervening pyridine rings.Preliminary X-ray analysis of dimetaxylylenetetra(2,6-lutidylene)tetramine. KC10 4 complex shows that K^+ ion locates in the central cavity of the cryptand.

合成了三维穴醚，其中桥头氮原子上的6个、8个或10个孤电子对或中间吡啶环都指向中心空穴，得到了6个苯环中的4个或全部6个被吡啶环取代的化合物作为它们的碱金属穴醚.增加吡啶环的数目可提高络合能力。二甲基亚苯基四（2，6-二甲基亚苯基）四胺的X射线分析KC 10 4络合物表明K^+离子位于穴状体的中心空腔中。

项目成果

Hiroyuki Takemura: Tetrahedron Lett.

竹村宏之：四面体莱特。

Mitsunori Tanaka: Chem. Lett.1673-1674 (1987)

田中光典：化学。

Teruo Shinmyozu: J.Org.Chem.,. 51. 1551-1555 (1986)

新明照夫：J.Org.Chem.,。

Teruo Shinmyozu: J.Org.Chem.,. 50. 1959-1963 (1985)

新明照夫：J.Org.Chem.,。

Masafumi Fukae: J.Incl.Phen.,. 2. 223-229 (1985)

Masafumi Fukae：J.Incl.Phen.，。