OCULAR SURFACE -physiological & Pathological Proterties-

眼表面最重要的特征之一是维持角膜的透明性，而角膜透明性是光学屈光的主要部分。另一个特点是面对外部环境，如物化刺激、异物和感染。对于眼表在这些条件下的足够功能，必须确定粘膜的防御机制和伤口愈合过程具有一定的特点。主要研究内容如下：1)眼表作为防御机制的场所；3)眼表粘蛋白的性质、细菌黏附和表型粘蛋白、表面型粘蛋白的膜活检、杯状细胞的粘蛋白分泌；2)眼表创面愈合方面的特点：角膜、角膜缘、结膜、眼表长期显微镜。结论：杯状细胞最重要的功能之一是为泪液提供粘蛋白，但在眼表防御机制中也起着重要作用。角膜、角膜缘和结膜通常共享眼表的分割功能，而它们却出人意料地适合于上皮层的伤口愈合。应认识结膜在角膜疾病中的意义

One of the most significant features of ocular surfacr is the maintenance of the conrneal transparency which plays a principal part of optical refraction. Another feature is that of facing to the external circumstance such as physical chemical stimulus, foreign bodies and infection. With regard to the enough function of ocular surface under these conditions, defence mechanism of mucous membrane and wound healing process must be assuemed to have some characteristics. Physiological & pathological properties have been studies as follows; I) Ocular surface as a place of defence mechanism; Nature of Ocular Mucins, bacterial Adhesion and Surface Mucins, Membrane Biopsies of Surface Mucins, Mucins Secretion of Goblet Cells II) Characteristics of Ocualr Surface on the Aspects of Wound Healing: Cornea, Limbus, Conjunctiva, Secular Microscopy of Ocular Surface. Conclusions: One of the most important functions of Goblet cells is to Supply of mucins into the tear, but it is essencially also of importance in playing a part of defence mechanism of ocular surface. Cornea, limbus and conjunctiva usually share divisional functions of ocular surface, While they are surprisingly suited for wound healing of epithelial layers. Significance of conjunctiva to the corneal diseases should be recognized