Analysis of voluntary movement mechanism using transcranial magnetic stimulation
经颅磁刺激随意运动机制分析
基本信息
- 批准号:04680127
- 负责人:
- 金额:$ 1.15万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for General Scientific Research (C)
- 财政年份:1992
- 资助国家:日本
- 起止时间:1992 至 1994
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
We recorded motor evoked potentials (MEPs) and H-reflexes from, flexor carpi radialis (FCR) muscle of eight normal adult subjects.Subiects were either at rest, or with the target muscle voluntarily contracted (10% max). A magnetic coil was used to deliver 20-30 stimuli and MEPs were recorded. H-reflexs were elicited by electrical stimulation of the median nerve (20-30 stimuli, 0.5-1.0 ms duration). The variability in amplitude, duration and area size of potentials was studied as excitability of human hand muscle motoneurons changed. The results were used to estimate whether MEP amplitude and H-reflex amplitude were an optimal index of excitability changes in the postsynaptic potentials of the human motoneuron pool. The variability in amplitude, duration and area size of the MEP were large than those of the H-reflex. Furthermore, there was a difference in the regression coefficient for amplitude and area size between H-reflex and MEP.These results indicate that there are differnt neurophysilogical mechanisms related to the production of excitatory postsynaptic potentials for the H-reflex and MEP,respectively.
我们记录了8名正常成年受试者的腕屈肌(FCR)的运动诱发电位(MEP)和H反射。受试者要么是静息状态,要么是目标肌主动收缩(最大收缩10%)。使用磁线圈传递20~30个刺激,记录MEP。电刺激正中神经(20~30个刺激,时程0.5~1.0ms)可诱发H-反射。研究了人手部肌肉运动神经元兴奋性改变时,电位的幅度、时程和面积的变化。结果被用来评估MEP波幅和H反射波幅是否是反映人运动神经元池突触后电位兴奋性变化的最佳指标。MEP的波幅、时程和面积的变异性大于H反射。此外,H反射和MEP的幅度和面积的回归系数也不同。这些结果表明,H反射和MEP的兴奋性突触后电位的产生分别存在不同的神经生理机制。
项目成果
期刊论文数量(16)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
笠井達哉: "反応時間法とH反射法を使ったヒト随意運動機能の解析" Japanese Journal of Sports Sciences. 13. 131-142 (1994)
Tatsuya Kasai:“使用反应时间法和 H 反射法分析人体自主运动功能”日本运动科学杂志 13. 131-142 (1994)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
笠井達哉: "ヒトの経頭蓋的大脳皮質刺激法" Japanese Journal of Sports Sciences. 12. 54-70 (1993)
Tatsuya Kasai:“人体经颅大脑皮层刺激”《日本运动科学杂志》12. 54-70 (1993)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
笠井達哉: "反応時間法とH反射法を使ったヒト随時運動機の解析" Japanese Journal of Sports Sciences. 13. 131-142 (1994)
Tatsuya Kasai:“使用反应时间法和 H 反射法分析人体自主运动”《日本运动科学杂志》13. 131-142 (1994)。
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- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Kasai, T. :"Transcranial Electric and Magnetic Stimulation in Intact Human Subject." Japanese Journal of Sports Sciences. 12. 54-70 (1993)
Kasai, T.:“对完整人体进行经颅电和磁刺激。”
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Kasai, T. :"An Analysis of Human Voluntary Movement by Reaction Time and H-reflex Technique." Japanese Journal of Sports Sciences. 13. 131-142 (1994)
Kasai, T.:“通过反应时间和 H 反射技术分析人类自主运动。”
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KASAI Tatsuya其他文献
KASAI Tatsuya的其他文献
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{{ truncateString('KASAI Tatsuya', 18)}}的其他基金
A study of human motor cognitive functions related to demonstration and imitation-Analysis of neurophysiological mechanisms-
与演示和模仿相关的人类运动认知功能研究-神经生理机制分析-
- 批准号:
16500380 - 财政年份:2004
- 资助金额:
$ 1.15万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Analysis of neurophysiological mechanisms in human motor imagery
人类运动想象的神经生理机制分析
- 批准号:
10680031 - 财政年份:1998
- 资助金额:
$ 1.15万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Neural mechanisms of anticipatory postural adjustment in human
人类预期姿势调整的神经机制
- 批准号:
07680119 - 财政年份:1995
- 资助金额:
$ 1.15万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
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