Disulfide Bonds and Protein Folding

这项工作将促进我们对蛋白质折叠的理解，这对生物技术具有重要意义，影响重组蛋白的商业生产（用于制药和生物医学应用）以及全球数千个使用重组技术的研究实验室。这项研究还可以为医学（治疗蛋白质错误折叠疾病，如阿尔茨海默氏症）和膜蛋白结构生物学做出贡献。这项工作可以通过可申请专利的成果产生长期的经济效益，并将通过产生高影响力的研究论文、为澳大利亚人提供培训以及与国际知名科学家建立联系而使社会受益。

This work will advance our understanding of protein folding, which has important implications in biotechnology, impacting on commercial production of recombinant proteins (for pharmaceutical and biomedical applications) and on 1000s of research laboratories worldwide that use recombinant technologies. This research could also contribute to medicine (new treatments for diseases of protein misfolding like Alzheimer's), and to membrane protein structural biology. This work could yield economic benefits in the long-term through patentable outcomes and will benefit the community by producing high impact research papers, providing training to Australians and forging links with renowned international scientists.