CNS participation in blood pressure charges at ventrolateral medulla compression of rat
中枢神经系统参与大鼠腹外侧延髓受压血压变化
基本信息
- 批准号:06671409
- 负责人:
- 金额:$ 1.34万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for General Scientific Research (C)
- 财政年份:1994
- 资助国家:日本
- 起止时间:1994 至 1995
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
(Materials & Methods)Thirty-four rat were anesthetized under respirator and oxygen flow adjusted to maintain blood gases and PH within physiological limits. The animals were placed prone to expose the ventrolateral medulla to permit insertion of silicone microballon beneath the axilla of the IXth & Xth cranial nerves. The sites of balloon compression were as followings : a) right ventrolateral medulla (Rt-VLM) with an electrolytic lesion at Cl-cell group, b) Rt-VLM without an electrolytic lesion, c) left (Lt) -VLM with an electrolytic lesion at C1 -cell group, d) Lt-VLM without an electrolytic lesion, e) Rt-&Lt-VLMs with bilateral electrolytic lesions at Cl-cell groups.(Results)Balloon inflation caused a significant elevated blood pressure not only Rt but also Lt-side compression. There were also no definite difference in changing blood pressure between with and without an electrolytic lesion at Cl-cell group.(Conclusion)These experimental results using rats did not support the clinical evidence, that was the relief of preoperative long-standing hypertension after the mobilization of an arterial loop on the area anterior to the left IXth & Xth cranial nerves.
(材料与方法)34只大鼠在呼吸机下麻醉,调整氧流量,维持血气和PH在生理范围内。将动物俯卧放置以暴露腹外侧髓质,以允许在第IX和第X脑神经的腋窝下插入硅胶微球。球囊压迫的部位如下:a)Cl-细胞组的右侧腹外侧延髓(Rt-VLM)有电解损伤,B)Rt-VLM无电解损伤,c)Cl-细胞组的左侧(Lt)-VLM有电解损伤,d)Lt-VLM无电解损伤,e)Cl-细胞组的双侧电解损伤的Rt-VLM和Lt-VLM。(结果)球囊扩张后不仅右侧血压明显升高,左侧血压也明显升高。Cl-细胞组电解损伤前后血压变化无明显差异。(结论)本实验结果不支持左第9、第10脑神经前动脉袢游离后术前长期高血压缓解的临床证据。
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Yamamoto I: "Microvascular decompression for hypertension" 9th Asian-Australasian Congress of Neurological Surgery (guest lecture). (1995)
Yamamoto I:“高血压的微血管减压”第九届亚洲-澳大利亚神经外科大会(客座演讲)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Yamamoto I: "Neurovascualr compression syndrome" 11th International Congress of Neurological Surgery (Iuncheon Seminor). (1997)
Yamamoto I:“神经血管压迫综合征”第 11 届国际神经外科大会(Iuncheon Seminor)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
YAMAMOTO Isao其他文献
YAMAMOTO Isao的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('YAMAMOTO Isao', 18)}}的其他基金
Development of innovative growth method of pure large protein crystal using strong magnetic field
利用强磁场开发纯大蛋白晶体的创新生长方法
- 批准号:
16K04946 - 财政年份:2016
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Potential of magnetic fluid for supercooling metal under magnetic field
磁流体在磁场下过冷金属的潜力
- 批准号:
24656012 - 财政年份:2012
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Prevention of child abuse: Studies on improvement of colic crying and fostering problems by the correction of the epiglottis and larynx (CGL).
预防虐待儿童:通过矫正会厌和喉(CGL)来改善绞痛哭闹和养育问题的研究。
- 批准号:
22610020 - 财政年份:2010
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Magnetic separation of DNA
DNA 的磁力分离
- 批准号:
20560044 - 财政年份:2008
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Molecular mechanism of intraplaque hemorrhage in carotid stenosis
颈动脉狭窄斑块内出血的分子机制
- 批准号:
19591693 - 财政年份:2007
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Basic investigation about relationship between Ankyloglossia with Deviation of the Epiglottis and Larynx and Sudden Death Infant syndrome(SIDS)
会厌喉偏位强舌症与婴儿猝死综合征(SIDS)关系的基础研究
- 批准号:
16590548 - 财政年份:2004
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Molecular biological study for mechanism of intraplaque hemorrhage in carotid stenosis
颈动脉狭窄斑块内出血机制的分子生物学研究
- 批准号:
16591451 - 财政年份:2004
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Digital of a Mobile Panoramic Radio-Apparatus and New System of Personal Identification
移动全景无线电设备的数字化和新的个人识别系统
- 批准号:
11672065 - 财政年份:1999
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
相似海外基金
Are changes in the properties of nucleus tractus solitarius inhibitory interneurons during postnatal development a risk factor for sudden infant death syndrome?
出生后发育过程中孤束核抑制性中间神经元特性的变化是否是婴儿猝死综合征的危险因素?
- 批准号:
22KK0120 - 财政年份:2022
- 资助金额:
$ 1.34万 - 项目类别:
Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
Physiological consequences of alcohol exposure on CRF 1 neurons in the nucleus tractus solitarius
酒精暴露对孤束核 CRF 1 神经元的生理影响
- 批准号:
10537984 - 财政年份:2022
- 资助金额:
$ 1.34万 - 项目类别:
The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
孤束核-中央杏仁核回路在酒精诱导的可塑性和饮酒行为中的作用
- 批准号:
10386868 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
孤束核-中央杏仁核回路在酒精诱导的可塑性和饮酒行为中的作用
- 批准号:
10158377 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
Amplification of satiation signaling by melanocortin-4 receptors in the nucleus tractus solitarius
孤束核中黑皮质素 4 受体放大饱足感信号
- 批准号:
10014592 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
Amplification of satiation signaling by melanocortin-4 receptors in the nucleus tractus solitarius
孤束核中黑皮质素 4 受体放大饱足感信号
- 批准号:
10389570 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
孤束核-中央杏仁核回路在酒精诱导的可塑性和饮酒行为中的作用
- 批准号:
10608946 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
The role of a nucleus tractus solitarius-central amygdala circuit in alcohol-induced plasticity and drinking behavior
孤束核-中央杏仁核回路在酒精诱导的可塑性和饮酒行为中的作用
- 批准号:
9926782 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
Amplification of satiation signaling by melanocortin-4 receptors in the nucleus tractus solitarius
孤束核中黑皮质素 4 受体放大饱足感信号
- 批准号:
10391115 - 财政年份:2019
- 资助金额:
$ 1.34万 - 项目类别:
NUCLEUS TRACTUS SOLITARIUS MELANOCORTIN SIGNALING IN THE CONTROL OF FOOD INTAKE
孤束核黑皮质素信号传导控制食物摄入
- 批准号:
8219209 - 财政年份:2010
- 资助金额:
$ 1.34万 - 项目类别: