Urodynamic change in patients with pelvic surgery

盆腔手术患者尿动力学变化

基本信息

批准号：
06671561
负责人：
KOBAYASHI Shinya
金额：
$ 1.22万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1995
项目状态：
已结题

项目摘要

'Post-radical prostatectomy incontinence' persisted in 45% and 85% of the patients at 3 and 12 months after the operation, respectively. The restoration of continence was as sociated with an improvement in urethral closing pressre in early postoperative poriod (3 months postop. in averrage) and an increase in vesical compliance later on. Postoperative urethral denervation supersensitivity suggests some neurological injury of alpha adrenergic system in the operative procedure.Uninary in continence recovered in 80% of the patients with Mainz type orthotopic bladder substitution at 16 months postoperatively under an averrage of 1.8 times of nocternal urination. In patients who recovered in continence lower amplitude of phasic contraction in pouchmetry, higher maxmal urethral closing pressure in urethral pressure profilometry and more prominent in crease in frequency of action potentials in external urethral sphicter electromyography in response to neobladder capacity and phasic contractio … More n were demonstrated compared to the patients with persistent incontinence.Urodynamic study in the patients with radical surgery for rectal cancer demonstrated the significantly better-reserved 1ower urinary tract function in patients with pelvic nerve preserved. Rate of normalization defined from urinary flow rate and residuals was 100% vs. 31% at 6 months postoperatively in patients with preserved vs. non-preserved pelvic nerve.Of patients with persisted voiding dysfunction for more than 12 months after radical surgery for rectal cancer, detrusor instability, vesical denervation supersensitivity were noted in 56%, 68%, 67% and 78%, respectively, indicating both vesical and urethral dysfunction contribute to voiding failure. 'Radical trasurethral resection of prostate', a modified transurethral sphincterotomy, was demonstrared to be effective treatment option that could reduce residual urine and consequently yield withdrawals of inttermitent self-catheterization without compromising urinary control in these patients. Less

手术后3和12个月，“后的前列腺切除术”分别在45％和85％的患者中持续了45％和85％。在术后早期的术后尿道关闭媒体（术后3个月）的尿道关闭媒体的改善和囊泡依从性的提高之后，尿道关闭压力有所改善，随后又增加了尿道关闭。术后尿道神经敏感性表明，在操作程序中，α肾上腺素系统的某些神经系统损伤。在80％的MAINZ类型的原位膀胱替代患者中，在16个月的80％患者中恢复了统一的持续性，以及1.8倍的Nocternal尿液尿布。在延性中恢复较低放大的患者中，囊袋中的阶段收缩较低，尿道压力条能学中的最大最大尿道关闭压力较高，并且在外部尿道Sphicter肌电图的折痕中更明显的尿道骨电位的折痕在外部尿道肌电图中响应新的板球能力和透明性范围，与跨患者相比，与NEOBLADDER的能力相比，相比之下。直肠癌表现出保留骨盆神经的患者的保留率明显较好的1次尿路功能。 Rate of normalization defined from urinary flow rate and residuals was 100% vs. 31% at 6 months as well as 6 months as well as non-preserved pelvic nerve.Of patients with persisted voiding dysfunction for more than 12 months after radical surgery for rectal cancer, detrusor instability, vesical denervation supersensitivity were noted in 56%, 68%, 67% and 78%, respectively, indicating both囊泡和尿道功能障碍有助于排空失败。事实证明，“一种修饰的前括约肌切除术”是一种有效的治疗选择，可以减少残留的尿液，因此在这些患者中不损害尿液控制的情况下，可以减少残留的尿液。较少的