Evaluation of trial mouthrinses with berberine hydrochloride

本研究旨在探讨口腔冲洗液对白色念珠菌、热带念珠菌、Igabrate念珠菌的抑菌作用，以及对口腔材料颜色稳定性和表面粗糙度的影响。含盐酸小檗碱的漱口液具有很强的抗真菌活性，是生药中的一种成分，其本身也具有抗真菌活性。体外实验证明，盐酸小檗碱漱口液具有抗真菌活性，并能保持口腔内的抗真菌活性因此，使用漱口水似乎是一个帮助，在预防溃疡性口腔炎

Candida species can be found in high frequency in denture plaque related t denture stomatitis.It is important to clean oral cavity as well as denture to preve denture stomatitis.This study investigated the antifungal activity of trial mouthrinses against C.albicans, C.tropicalis, and C.lgabrate and the effects on color stability and surface roughness of dental materials. Trial mouthrinses contain berberine hydrochloride whi is a component of crude drugs, that have strong antifungal activity, and has antifungal activity itself.Trial mouthrinses showed fungicidal, fungistatic, and postantifungal activity had no effect on color stability and surface roughness of dental materials.In vitro studies proved that the trial mouthrinses with berberine hydrochlor had antifungal activity and ability to keep the postantifungal activity in oral cavity Hence, use of the mouthrinses seems to be a help in preventing detnure stomatitis