Anticaries Efficacy of <Phytic Acid-Stannous Fluoride> Primer

<植酸-氟化亚锡>底漆的防龋功效

• 批准号: 06671974
• 负责人: HIRABAYASHI Shigeru
• 金额: $ 1.15万
• 依托单位: Tsurumi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06671974/
• 关键词: Anticaries efficacy; Remineralization; Tooth conditioner; Primer; Phytic acid; Stannous fluoride; フッ化錫

The <Phytic acid (PYA)-Stannous Fluoride (SnF_2)> primer has been developed in our department as a tooth conditioner for bonding dental adhesives to tooth substrates. The treatment with this primer requires two steps, a first treatment with 7% aqueous solution of PYA and a second treatment with 3% aqueous solution of SnF_2. Therefore, it is expected that the caries resistance of teeth treated with SnF_2 at second step is improved. This primer is called 7PYA+SnF_2 primer. In this study, the effect of SnF_2 on the remineralization process of enamel treated with 7PYA+SnF_2 primer was investigated by comparing with the other treatments commonly used in dentistry.The tooth conditioners tested were a 10% and a 40% aqueous solution of phosphoric acid, an aqueous solution containing 10% citric acid and 3% FeCl_3,7PYA+SnF_2 primer, and a 7% aqueous solution of PYA as its control. The bovine enamel treated with each tooth conditioner was stored in the remineralization solution prepared according … More to the prescription of ten Cate et al for seven days. The remineralization process of tretaed enamel was evaluated by Knoop hardness (KHN) measurment and SEM observation. The KHNs of enamel treated with conditioners were down to ab.25-40% of that of sound enamel. However, the KHNs were recovered to ab.60-70% after 1 day storage in the remineralization solution in all treatments except 7PYA+SnF_2 primer and did not increase remakably after that. The formation of crystals like hydroxyapatite was found on these enamel surfaces after 1 day storage by SEM observation. On the other hand, the KHN of enamel treated with 7PYA+SnF_2 primer was recovered to ab 30-40% only after seven days. However, the acid-proof layr, which could not be dissolved even with 0.05-N hydrochloric acid and had ab. 5mum in thickness, was found on its surface by SEM observation. This layr also was found immediately after the treatment with 7PYA+SnF_2 primer, but not found in the other treatment. These results suggested that the acid-proof layr controlled the formation of hydroxyapatite, and the 7PYA+SnF_2 primer had an anticaries efficacy. Less

在我们的部门开发了<植酸（PYA） - 静态氟化物（SNF_2）>底漆，作为将牙齿粘合剂粘合到牙齿底物的牙齿护发素。使用该底漆的处理需要两个步骤，第一次使用7％的Pya水溶液和SNF_2的3％水溶液进行第二次处理。因此，预计在第二步中用SNF_2处理的牙齿的携带能力得到改善。该底漆称为7Pya+SNF_2底漆。 In this study, the effect of SnF_2 on the reminderalization process of enamel treated with 7PYA+SnF_2 primer was investigated by comparing with the other treatments commonly used in dentistry.The tooth conditioners tested were a 10% and a 40% aqueous solution of phosphoric acid, an aqueous solution containing 10% citric acid and 3% FeCl_3,7PYA+SnF_2 primer, and a 7% aqueous solution pya作为控制。用每种牙齿护发素处理的牛搪瓷存储在提醒溶液中，根据……更多的cate等人的处方7天。通过knoop硬度（KHN）测量和SEM观察评估了通知搪瓷的提醒过程。用护发素处理的搪瓷的khns降低到AB。25-40％的声音搪瓷。但是，在1天存储后，将KHN回收为60-70％。通过SEM观察，在1天存储后，在这些搪瓷表面上发现了晶体等晶体的形成。另一方面，仅在7天后才将用7Pya+SNF_2底漆处理的搪瓷KHN回收至30-40％。但是，即使使用0.05-N盐酸，也无法溶解的酸性layr，并具有AB。通过SEM观察发现了5mum的厚度，在其表面上发现。在用7PyA+SNF_2底漆处理后，该Layr也立即发现，但在另一种处理中未发现。这些结果表明，酸性Layr控制了羟基磷灰石的形成，而7pya+SNF_2底漆具有抗精性效率。较少的

项目成果

Shigeru Hirabayashi: "Influences of various tooth conditioners on the remineralization of enamel in vitro -Evaluation by KHN and SEM observation-" J J Dent Mater. Vol.16 Special 29. 54 (1997)

Shigeru Hirabayashi：“各种牙齿调理剂对体外牙釉质再矿化的影响 - 通过 KHN 和 SEM 观察进行评估 -” J J Dent Mater。

平林茂: "in vitroにおける酸処理エナメル質の再石灰化に及ぼす各種前処理剤の影響-ヌープ硬さとSEM観察による評価-" 歯科材料・器械. 16(S29). 54 (1997)

Shigeru Hirabayashi：“各种预处理剂对酸处理牙釉质体外再矿化的影响 - 通过努普硬度和 SEM 观察进行评估 -”牙科材料和仪器 16（S29）。