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ESTIMATION OF MUSCULAR ENERGY METABOLISM DURING EXERCISE AND EFFECTS OF MUSCLE TRAINING STUDIED BY ^<31>P-NMR SPECTROSCOPY.

通过 31 P-NMR 光谱研究运动期间肌肉能量代谢的估计和肌肉训练的效果。

基本信息

批准号：
06680102
负责人：
HIRAKAWA Kazufumi
金额：
$ 1.22万
依托单位：
FACULTY OF HUMAN DEVELOPMENT,KOBE UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1995
项目状态：
已结题

项目摘要

We examined responses in muscular energy metabolism during exercise and effects of muscle training on muscular energy metabolism using ^<31>P-NMR spectroscopy. The results were summarized as follows :1. During a progressive exercise, intracellular pH decreased gradually with an increase of work load, and then a rapid acidification was observed at about 57% of the maximal work load (6.9 of pH value). This threshold in intracellular pH correlated significantly to thresholds detected from non-linear increases in integrated electromyogram and expired gas parameters.2. In a subnormal muscle temperature condition, intracellular pH during an anaerobic exercise showed the higher value than that at a control condition, and the anaerobic endurance performance decreased significantly. These results suggest that glycolytic energy pathway would be inhibited under the subnormal muscle temperature condition. On the contrary, intracellular pH during an aerobic exercise preceded by a warm-up exercise s … More howed the higher value than that of the control condition. This result means that the oxidative capacity in the muscle is improved by performing a warm-up exercise.3. As a result of an aerobic training (the exercise intensity of 30-40% MVC,the frequency of 4 days/week, and the 15 week training period), the oxidative capacity in muscle was significantly improved as shown by a decrease in Pi/PCr ratio and an increase in intracellular pH at the same sub-maximal work load. And also, the improvement of the endurance performance showed to paralleled to lesser degree of the acidification in the muscle.4. As a result of a power training (the exercise intensity of 10 repetition maximum, the frequency of 4 days/week, and the 5 week training period), muscular power output and anaerobic endurance time increased significantly. However, concerning phosphorus metabolic changes, it only occurred that %PCr during the anaerobic exercise increased due to the training. There was no difference in the intracellular pH between the pre- and the post-training. These results suggest that the increase in the anaerobic performance might be attributable to the increase of phosphagen, the improvement of glycolytic capacity, or the increase in creatine kinase activity in the muscle due to the training. Less

我们使用1HP-NMR光谱检查了运动期间肌肉能量代谢的反应以及肌肉训练对肌肉能量代谢的影响<31>。主要研究结果如下：1.在渐进运动过程中，随着运动负荷的增加，细胞内pH值逐渐下降，然后在最大运动负荷的57%左右（pH值为6.9）时观察到快速酸化。细胞内pH的阈值与综合肌电图和呼气参数的非线性增加检测到的阈值显著相关。在低于正常肌肉温度的条件下，无氧运动期间的细胞内pH值显示出高于对照条件下的值，并且无氧耐力性能显著降低。这些结果表明，在低于正常的肌肉温度条件下，糖酵解能量途径将受到抑制。相反，细胞内pH值在有氧运动之前的热身运动， ...更多信息显示出比对照条件更高的值。这一结果意味着通过进行热身运动，肌肉中的氧化能力得到了改善。3.作为有氧训练（30- 40%MVC的运动强度，4天/周的频率和15周的训练期）的结果，肌肉中的氧化能力显著改善，如在相同的次最大工作负荷下Pi/PCr比率的降低和细胞内pH的增加所示。耐力成绩的提高也表现为肌肉酸化程度的降低.作为力量训练的结果（最大重复10次的运动强度，4天/周的频率，和5周的训练期），肌肉功率输出和无氧耐力时间显著增加。然而，关于磷代谢的变化，它只发生%PCr在无氧运动期间增加，由于训练。有没有在细胞内的pH值之间的训练前和训练后的差异。这些结果表明，无氧性能的提高可能是由于磷酸原的增加，糖酵解能力的改善，或肌酸激酶活性的增加，在肌肉中由于训练。少