Biological Relatedness and Prehistoric Population Structure in Southern Germany in the Light of High Resolution Palaeogenomes from Caves of the Franconian Jura

根据法兰克侏罗山洞穴的高分辨率古基因组研究德国南部的生物相关性和史前人口结构

• 批准号: 447467896
• 负责人: Professor Dr. Joachim Burger
• 金额: --
• 依托单位: Computational and Molecular Population Genetics
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/447467896?language=en
• 关键词: Biological; Relatedness; Prehistoric; Population; Structure

In this research project, prehistoric human skeletal finds from caves of the Frankenalb will be genetically investigated in order to reconstruct the population structure and biological history of this region during the pre-Christian millennia with the help of a combination of high and low coverage genomes. The anthropological finds of the northern and middle Frankenalb between Forchheim, Nürnberg and Amberg are likely to be chronologically heterogeneous, but date predominantly to the Iron Age. The precise archaeological and anthropological background will be investigated in a second project submitted in parallel by Andreas Schäfer from the University of Bamberg. The genetic investigations in Mainz will be carried out on two different levels: in a first step, family relationships between the individuals will be reconstructed in order to investigate the question of how the caves were used. In a second step, high-resolution genomes will be analysed to characterise the population dynamics of the millennia before Christ in southern Germany on a large scale and in comparison, to neighbouring regions. In total, 70 complete genomes will be analysed for this purpose, 20 of them in high-resolution sequencing depth. The high coverage genomes will be used to uncover more subtle population structures and distant kinship relationships.

在这个研究项目中，将对弗兰肯白洞穴中发现的史前人类骨骼进行遗传学研究，以便在高覆盖率和低覆盖率基因组的帮助下重建该地区在基督教前千年的人口结构和生物历史。在福希海姆、纽伦堡和安贝格之间的北方和中部弗兰肯阿尔布的人类学发现可能在时间上是不均匀的，但主要是在铁器时代。精确的考古学和人类学背景将在班贝格大学的Andreas Schäfer同时提交的第二个项目中进行调查。在美因茨进行的基因调查将在两个不同的层面上进行：第一步，将重建个体之间的家庭关系，以调查洞穴是如何使用的问题。第二步，将对高分辨率基因组进行分析，以大规模地了解德国南部基督诞生前几千年的人口动态，并与邻近地区进行比较。总共将分析70个完整的基因组，其中20个将进行高分辨率测序。高覆盖率的基因组将用于揭示更微妙的人口结构和遥远的亲属关系。