权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Developmental study of the specific prescription program for the improvement of mental health trouble in human

改善人类心理健康问题的具体处方方案的开发研究

基本信息

批准号：
14208005
负责人：
SHIBAYAMA Hidetaro
金额：
$ 30.53万
依托单位：
National Institute of Fitness and Sports in Kanoya
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
2002
资助国家：
日本
起止时间：
2002 至 2005
项目状态：
已结题

项目摘要

The overall purpose of this study was to obtain experimental evidences to develop a specific prescription program for the people who have a trouble in mental health. We observed the effects of several exercise combined-programs on the brain tissue, cardiovascular systems, autonomic nervous function, and skeletal muscles of human subjects and experimental animals. The main results of the human studies are summarized as follows.We investigated the effects of exercise on myocardial glucose uptake and whether the pattern of glucose uptake is the same as in skeletal muscle. Glucose uptake was measured using positron emission topography (PET) and 2-[^<18>F] fluoro-2-deoxy-D-glucose. As compared to the resting state, exercise doubled myocardial glucose uptake at the 30% and 55% intensity levels, while at the 75% intensity level glucose uptake was reduced significantly compared to the lower exercise intensities. At rest and during low-intensity exercise, myocardial glucose uptake was inversely … More associated with circulating levels of free fatty acids. However, during higher exercise intensities when plasma lactate concentrations increased significantly, this association disappeared. This finding suggests that the increased myocardial energy that is needed during high-intensity exercise is supplied by substrates other than glucose.Reductions in the compliance of central arteries exert a number of adverse effects on systemic cardiovascular function and diseases. Using the cross-sectional study design, we determined the relation between chronic resistance training and carotid arterial compliance. (1)resistance exercise training is associated with the smaller central arterial compliance in health middle-aged men ; (2)age-related reductions in arterial compliance was greater in resistance-trained men than in sedentary men ; (3)the lower arterial compliance in the resistance-trained men is associated with left ventricular hypertrophy. In marked contrast to the beneficial effect of regular aerobic exercise, the present findings are not consistent with the idea that resistance exercise training exerts beneficial influences on arterial wall buffering functions. Less

本研究的主要目的是为心理健康问题患者制定具体的处方方案提供实验依据。观察了几种运动组合方案对人体和实验动物的脑组织、心血管系统、自主神经功能和骨骼肌的影响。人体研究的主要结果总结如下：我们研究了运动对心肌葡萄糖摄取的影响，以及葡萄糖摄取的模式是否与骨骼肌相同。使用正电子发射地形图（PET）和2-[13 <18>F]氟-2-脱氧-D-葡萄糖测量葡萄糖摄取。与静息状态相比，在30%和55%强度水平下，运动使心肌葡萄糖摄取增加一倍，而在75%强度水平下，与较低运动强度相比，葡萄糖摄取显著降低。在休息时和低强度运动时，心肌葡萄糖摄取呈反比， ...更多信息与游离脂肪酸循环水平有关。然而，在较高的运动强度时，血浆乳酸浓度显着增加，这种关联消失。这一发现表明，在高强度运动期间所需的增加的心肌能量是由葡萄糖以外的底物提供的。中心动脉顺应性的降低对全身心血管功能和疾病产生了许多不利影响。采用横断面研究设计，我们确定了慢性阻力训练和颈动脉顺应性之间的关系。（1）抗阻训练与健康中年男性中心动脉顺应性降低有关;（2）抗阻训练组动脉顺应性的年龄相关性降低大于久坐组;（3）抗阻训练组动脉顺应性降低与左心室肥厚有关。与常规有氧运动的有益效果形成鲜明对比的是，本研究结果与抗阻运动训练对动脉壁缓冲功能产生有益影响的观点不一致。少

项目成果

期刊论文数量（78）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Fujimoto, T., Kemppainen, J., Kalliokoski, K.K., Nuutila, P., Ito, M.: "Skeletal muscle glucose uptake response to exercise in trained and untrained men."Med.Sci.Sports Exerc.. 35. 777-783 (2003)

Fujimoto, T.、Kemppainen, J.、Kalliokoski, K.K.、Nuutila, P.、Ito, M.：“受过训练和未经训练的男性骨骼肌葡萄糖摄取对运动的反应。”Med.Sci.Sports Exerc.. 35. 777

DOI：
发表时间：
期刊：
影响因子：
0
作者：
通讯作者：

Fluctuations in carotid arterial distensibility during the menstrual cycle do not influence cardiovagal baroreflex sensitivity.

月经周期期间颈动脉扩张性的波动不影响心脏迷走神经压力反射敏感性。

DOI：
发表时间：
2006
期刊：
Acta Physiol (Oxf). 186
影响因子：
0
作者：
Hayashi;K.;Miyachi;M.;Seno;N.;Takahashi;K.;Yamazaki;K.;Sugawara;J.;Yokoi;T;Onodera;S.;Mesaki;N.
通讯作者：
N.

藤本敏彦, 伊藤正敏: "非侵襲的手法による筋の糖・脂質代謝と運動"体育の科学. 52. 429-435 (2002)

Toshihiko Fujimoto、Masatoshi Ito：“使用非侵入性方法进行肌肉葡萄糖/脂质代谢和运动”《体育科学》52. 429-435 (2002)。