Physiological role(s) of the immune system and tissue-specific stem cells in the plasticity of skeletal muscles-their application to the development of sports sciences-

骨骼肌具有很大的可塑性。预防肌肉萎缩并伴随收缩功能下降的对策的研究是预防医学和健康体育科学中维护身体活动和生活质量的重要问题之一。然而，目前还没有有效的对策。目前的研究表明，骨骼肌的可塑性可以受到免疫系统和肌肉特异性干细胞(即所谓的卫星细胞)的刺激。本研究的证据可能有助于对萎缩和损伤的骨骼肌的抑郁肌肉功能进行有效的康复。

Skeletal muscle has a large plasticity. The development of a countermeasure for the prevention of muscle atrophy, which is accompanied with the depressed contractile function, is one of important issues for the maintenance of physical activity and Quality of Life (QOL) in the preventive medicine as well as in Health and Sports Sciences. However, there is no effective countermeasure. The present study revealed that skeletal muscle plasticity could be regulated by the stimulations of both the immune systems and muscle specific stem cells, so called satellite cells. Evidences from the present study might be useful for the development of effective rehabilitations for the depressed muscle function in both atrophied and injured skeletal muscles.