Study on the structure and funciotion of supramolecular flagellar motor
Study on the structure and funciotion of supramolecular flagellar motor
批准号:
18207011
负责人:
HOMMA Michio
金额:
$31.45万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2009
中文摘要
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英文摘要
The proteins, PomA, PomB, MotX and MotY have been identified as the motor proteins that are necessary for the flagella rotation. The T ring newly found by us is necessary for the assembly. The structure of the component protein, MotY, of the T ring is determined with a 2.9 Å resolution. We proposed the molecule dynamic model of the flagella motor proteins to assemble as a functional motor. We showed that the C ring structure was easily dissociated from the flagella base body. Furthermore we found that FlgT was the basal body component to construct a ring outside of the LP ring. The ring was named an H ring. The new ring may contribute on the Vibro motor function as a strong shaft to support the high-speed rotation of the motor.
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Cell-free synthesis of the torque-generating membrane proteins, PomA and PomB, of the Nat-driven flagellar motor in Vibrio alginolyticus.
溶藻弧菌 Nat 驱动的鞭毛马达的扭矩产生膜蛋白 PomA 和 PomB 的无细胞合成。
DOI:
--
发表时间:
2008
期刊:
J. Biochem. 144(5)
影响因子:
--
作者:
[Terashima, H., Abe-Yoshizumi, R., Kojima, S., Homma, M.]
通讯作者:
M.
In vivo架橋を用いた大腸菌走化性における受容体クラスターの構造機能連関の解析
利用体内交联分析大肠杆菌趋化性受体簇的结构-功能关系
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[M. Isobe, M. Kurono, K. Tsuboi< and A. Takai, 入枝泰樹]
通讯作者:
入枝泰樹
DOI:
--
发表时间:
期刊:
PomA and PomB, of the Na^+-driven flagellar motor in Vibrio alginolyticus. J Biochem 144
影响因子:
--
作者:
[Terashima H, Abe-Yoshizumi R, Kojima S, Homma M.]
通讯作者:
Homma M.
Roles of charged residues of rotor and stator in flagellar rotation : Comparative study using H^+-driven and N^+-driven motors in Escherichia coli.
转子和定子带电残基在鞭毛旋转中的作用:在大肠杆菌中使用 H^ 驱动和 N^ 驱动电机的比较研究。
DOI:
--
发表时间:
2006
期刊:
J. Bacteriol. 188
影响因子:
--
作者:
[Yakushi, T., Yang, J.-H., Fukuoka, H., Homma, M., Blair D.]
通讯作者:
Blair D.
DOI:
10.1111/j.1365-2958.2009.06802.x
发表时间:
2009-08-01
期刊:
MOLECULAR MICROBIOLOGY
影响因子:
3.6
作者:
[Kojima, Seiji, Imada, Katsumi, Namba, Keiichi]
通讯作者:
Namba, Keiichi
共 20 条
Analysis of the structural dynamics of the flagellar motor proteins using NMR
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批准号:24657099
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2012
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负责人:HOMMA Michio
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依托单位:
Study on the dynamic structure change of membrane supramolecular flagellar motor and the force generation
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批准号:23247024
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.87万
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财政年份:2011
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负责人:HOMMA Michio
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依托单位:
Roles of the chemotaxis and the motility by flagella on environmental response of Vibio cells
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批准号:16017241
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$9.41万
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财政年份:2004
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负责人:HOMMA Michio
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依托单位:
Study on structure and function of force-generating proteins in ion-driven flagellar motor
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批准号:13308038
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$33.7万
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财政年份:2001
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负责人:HOMMA Michio
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依托单位:
Energy Transduction in Sodium Driven-flagagellar Motor
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批准号:09480174
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$8.13万
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财政年份:1997
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负责人:HOMMA Michio
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依托单位:
Study on the Vibro flagellar motor as the mechanosensor
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批准号:06808064
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1994
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负责人:HOMMA Michio
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依托单位:
海外基金