Creative and Highly Efficient Synthesis of Biologically Functional Molecules and Its Application in Drug Development Study

为了获得一系列具有复杂和高维结构的天然产物，显示出有趣的生物活性，但在自然界中仅少量存在，生物体功能分子，并构建其关键结构，已经建立了创造性和环境友好的合成方法。基于这些合成的新化合物组，与具有原始药物评估系统的其他研究小组和研究所合作，推进了一项药物开发研究，旨在创建显示新机制的新药物靶点。

Creative and environmentally friendly synthetic methods have been established for the purpose of obtaining a series of natural products which have complicated and high dimensional structures showing interesting biological activities but occurring only in small amounts in nature, living body-functioned molecules, and for construction of their key structures. Based on these groups of new compounds synthesized, a drug development study toward a creation of novel medicinal targets that show new mechanisms has been advanced in collaboration with other research groups and institutes having original drug evaluation systems.