Research of a novel hard-tissue biodegradable adhesive as a drug delivery carrier.

骨和牙齿等硬组织的修复需要一种生物粘合剂。以磷酸化普鲁兰多糖为基础，研制了一种新型的硬组织生物降解胶粘剂。本研究以磷酸化普鲁兰多糖为载体，考察其作为药物释放载体的性能。因此，磷酸化普鲁兰多糖生物粘附剂是一种理想的药物释放载体材料。

A bioadhesive that can be bonded to hard tissue such as bone and tooth, is highly needed for hard-tissue repair in orthopaedic medicine and dentistry. We developed a novel hard-tissue biodegradable adhesive on basis of phosphorylated pullulan. In this study, we examined the property of phosphorylated pullulan bioadhesive as a drug delivery carrier. As a result, phosphorylated pullulan bioadhesive appears to be an ideal material as a drug delivery carrier.