a novel approach to create and characterize bone and bone marrow by the combination of tissue engineering and hematology
a novel approach to create and characterize bone and bone marrow by the combination of tissue engineering and hematology
批准号:
21860051
负责人:
KOHARA Hiroshi
金额:
$1.71万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
Angiogenesis was induced around the implanted site of gelatin hydrogels incorporating Substance P, a member of tachykinin family neuropeptides. In addition, accumulation of granulocytes, one of the circulating cells with angiogenic activities, around the implanted sites was observed. It is conceivable that the controlled release of SP efficiently induced the recruitment and the subsequent activation of granulocytes from the blood circulation into the site implanted, resulting in enhanced angiogenesis.
期刊论文(7)
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The controlled release of neuropeptide induces angiogenesis.
神经肽的受控释放诱导血管生成。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kohara, H., Yamamoto, M., Tabata, Y.]
通讯作者:
Y.
ゼラチンハイドロゲルを用いた神経ペプチドの徐放による血管新生誘導
使用明胶水凝胶持续释放神经肽诱导血管生成
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[C.Klein, W.E.Sachs, U.Henne, Y.Egami, H.Mai, V.Ondrus, Y.Beifuss, 小原洋志]
通讯作者:
小原洋志
徐放化神経ペプチドによる血管新生の誘導
缓释神经肽诱导血管生成
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[小原洋志, 田畑泰彦]
通讯作者:
田畑泰彦
DOI:
10.1016/j.biomaterials.2010.07.079
发表时间:
2010-11-01
期刊:
BIOMATERIALS
影响因子:
14
作者:
[Kohara, Hiroshi, Tajima, Shuhei, Tabata, Yasuhiko]
通讯作者:
Tabata, Yasuhiko
ゼラチンハイドロゲルを用いた神経ペプチド徐放システムによる血管新生誘導
使用明胶水凝胶通过持续神经肽释放系统诱导血管生成
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[小原洋志, 田畑泰彦]
通讯作者:
田畑泰彦
海外基金