Research of the new target for the treatment of disorders of nerves
Research of the new target for the treatment of disorders of nerves
批准号:
22890107
负责人:
OKADA Kiyoshi
金额:
$1.96万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
In this research, we found that the Akt/ mTOR signaling pathway related with Icmtcontrols neurite outgrowth and neuronal apoptosis. We believe that Icmt has apotential to become a new target to treat several nervous disorders, and furtherinvestigation of the effects of Icmt may reveal new insights into nerveregeneration and the treatment of several nervous diseases and injuries.
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Methylcobalamin promotes neurite outgrowth through Akt/mTOR signaling pathway in cerebellar granule neurons.
甲钴胺通过小脑颗粒神经元中的 Akt/mTOR 信号通路促进神经突生长。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[村木重之, 阿久根徹, 岡敬之, 中村耕三, 川口浩, 吉村典子, Kiyoshi Okada]
通讯作者:
Kiyoshi Okada
MethylcobalaminはAkt/mTORシグナル伝達を介して神経軸索伸展を促進する
甲钴胺通过 Akt/mTOR 信号传导促进神经元轴突延伸
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Rika Yuliwulandari, Kouyuki Hirayasu, 他7名, 岡田潔]
通讯作者:
岡田潔
Akt/mTOR signaling pathway regulates neurite outgrowth in cerebellar granule neurons affected by methylcobalamin.
Akt/mTOR 信号通路调节受甲钴胺影响的小脑颗粒神经元的神经突生长。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[岡田潔, 他, Kiyoshi Okada]
通讯作者:
Kiyoshi Okada
Methylcobalamin promotes neurite outgrowth with the activation of Akt/mTOR.
甲钴胺通过激活 Akt/mTOR 促进神经突生长。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[岡田潔, 他, Kiyoshi Okada, Kiyoshi Okada]
通讯作者:
Kiyoshi Okada
p70 ribosomal S6 protein kinaseの活性化とmethylcobalamin作用機序の関係
p70核糖体S6蛋白激酶激活与甲钴胺作用机制的关系
DOI:
--
发表时间:
2011
期刊:
末梢神経
影响因子:
--
作者:
[岡田潔, 他]
通讯作者:
他
共 10 条
Preparation of Intelligent Water Vapor Control Material by Selective Leaching Method
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批准号:09450240
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.94万
-
财政年份:1997
-
负责人:OKADA Kiyoshi
-
依托单位:
Preparation of Porous Mullite Fibers for Support of Environmental Catalyst
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批准号:08555152
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$12.74万
-
财政年份:1996
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负责人:OKADA Kiyoshi
-
依托单位:
Preparation of New Molecular Sieve Material by Selective Leaching Method
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批准号:07455263
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.14万
-
财政年份:1995
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负责人:OKADA Kiyoshi
-
依托单位:
Preparation of Long Alumina Whiskers
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批准号:04555184
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$2.94万
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财政年份:1992
-
负责人:OKADA Kiyoshi
-
依托单位:
Study on Formation Condition and Cation Site Occupancy in Garnets
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批准号:63460052
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.03万
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财政年份:1988
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负责人:OKADA Kiyoshi
-
依托单位:
海外基金