Increased occlusal vertical dimension induces modulation of masticatory feedforward control
Increased occlusal vertical dimension induces modulation of masticatory feedforward control
批准号:
23890056
负责人:
SHIBATA Mai
金额:
$2.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
以往的研究表明,初级运动皮层(M1)的功能可塑性与运动技能学习和环境变化有关。增加咬合垂直尺寸(iOVD)可以调节咀嚼,如在咀嚼周期,周期,和下颌肌梭的放电特性。然而,关于iOVD后面部初级运动皮层(face-M1)内运动表征的变化知之甚少。本研究的目的是使用皮质内微刺激(ICMS)确定iOVD对面部M1的影响。在iOVD组中,上颌磨牙用丙烯酸树脂构建2 mm。在iOVD后1、2和8周,记录ICMS在右侧面M1内诱发的左(LAD)和右(RAD)前二腹肌(AD)、咬肌和颏舌肌(GG)的肌电图(EMG)活动。IOVD与ICMS诱发LAD和/或GG EMG活动的面M1内的部位数量显著增加相关,并且在1周和2周时RAD和LAD肌肉的重心发生侧向移位,但在8周时不相关。这些发现表明,大鼠面M1内的时间依赖性神经可塑性变化与iOVD相关。这可能与动物适应口腔环境变化的能力有关。
英文摘要
Previous studies have demonstrated that functional plasticity in the primary motor cortex (M1) is related to motor-skill learning and changes in the environment. Increased occlusal vertical dimension (iOVD) may modulate mastication, such as in the masticatory cycle, cycle, and the firing properties of jaw-muscle spindles. However, little is known about the changes in motor representation within the face primary motor cortex(face-M1) after iOVD. The purpose of the present study was to determine the effect of iOVD on the face-M1 using intracortical microstimulation (ICMS). In an iOVD group, the maxillary molars were built-up by 2 mm with acrylic. The electromyographic (EMG) activities from the left (LAD) and right (RAD) anterior digastric (AD), masseter and genioglossus (GG) muscles elicited by ICMS within the right face-M1 were recorded 1, 2 and 8 weeks after iOVD. IOVD was associated with a significant increase in the number of sites within the face-M1 from which ICMS evoked LAD and/or GG EMG activities, as well as a lateral shift in the center of gravity of the RAD and LAD muscles at 1 and 2 weeks, but not at 8 weeks. These findingssuggest that a time-dependent neuroplastic change within the rat face-M1 occurs in association with iOVD. This may be related to the animal’s ability to adapt to a change in the oral environment.
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DOI:
10.1016/j.bbr.2011.11.013
发表时间:
2012-03-17
期刊:
BEHAVIOURAL BRAIN RESEARCH
影响因子:
2.7
作者:
[Kato, C., Fujita, K., Ono, T.]
通讯作者:
Ono, T.
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Mai Shibata, Kazuo Shimazaki, Ikuo Yonemitsu, Susumu Omura, Takashi Ono. A]
通讯作者:
Takashi Ono. A
DOI:
10.1016/j.archoralbio.2014.02.013
发表时间:
2014-05-01
期刊:
ARCHIVES OF ORAL BIOLOGY
影响因子:
3
作者:
[Funaki, Yukiha, Hiranuma, Maya, Ono, Takashi]
通讯作者:
Ono, Takashi
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[MaiShibata, Kazuo Shimazaki, Ikuo Yonemitsu, Susumu Omura, Takashi Ono]
通讯作者:
Takashi Ono
咬合高径増加がラット大脳皮質一次運動野顎顔面領域における機能局在に与える影響
咬合高度增加对大鼠大脑皮层初级运动皮层颌面部功能定位的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[加藤千帆, 藤田紘一, 藪下忠親, 内藤聡美, 柴田真衣, 石田宝義, 小海暁, 小野卓史]
通讯作者:
小野卓史
Statistical analysis of switching states in stock market
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批准号:21730256
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$0.75万
-
财政年份:2009
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负责人:SHIBATA Mai
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依托单位: