200 keV Cryo Transmission Electron Microscope

应用现代低温电子显微镜(CRYO-TEM)进行单粒子分析和低温层析成像。对于数据的处理，计算集群是应用程序的一部分。获得低温透射电子显微镜是新任命的阿恩·莫勒教授(主要申请人)的一部分，并随之而来的是结构生物系的建立。作为一个平台，这些设备将成为奥斯纳布吕克大学优秀基础设施的一部分，那里已经建立了必要的房间。在Möler小组，该设备将用于确定膜蛋白的结构和功能，特别是与其脂环境有关的结构和功能。这种关注也是奥斯纳布吕克大学的经典关注点，这让我们期待着该设备的密集跨学科使用。低温透射电子显微镜将补充最近完成的CellNanos研究大楼和其中已有的高分辨率显微镜技术，从而填补现有的一大空白。

A modern cryo transmission electron microscope (cryo-TEM) for single particle analysis and cryo tomography is applied for. For the processing of the data, a computing cluster is part of the application. The acquisition of the cryo-TEM is part of the new appointment of Prof. Dr. Arne Möller (main applicant) and the accompanying establishment of the Department of Structural Biology. As a platform, the devices will become part of the excellent infrastructure at the University of Osnabrück, where the necessary rooms have already been created. In the Möller group, the device will be used to determine the structure and function of membrane proteins, especially in relation to their lipid environment. This focus is also a classical focus at the University of Osnabrück, which leads us to expect an intensive interdisciplinary use of the device. The cryo-TEM will complement the recently completed CellNanOs research building and the microscope techniques already available in it with high resolution, thus closing a large existing gap.