200 keV Cryo Transmission Electron Microscope

200 keV 冷冻透射电子显微镜

• 批准号: 455249646
• 金额: --
• 依托单位: Universität Osnabrück
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/455249646?language=en
• 关键词: 200; keV; Cryo; Transmission; Electron

A modern cryo transmission electron microscope (cryo-TEM) for single particle analysis and cryo tomography is applied for. For the processing of the data, a computing cluster is part of the application. The acquisition of the cryo-TEM is part of the new appointment of Prof. Dr. Arne Möller (main applicant) and the accompanying establishment of the Department of Structural Biology. As a platform, the devices will become part of the excellent infrastructure at the University of Osnabrück, where the necessary rooms have already been created. In the Möller group, the device will be used to determine the structure and function of membrane proteins, especially in relation to their lipid environment. This focus is also a classical focus at the University of Osnabrück, which leads us to expect an intensive interdisciplinary use of the device. The cryo-TEM will complement the recently completed CellNanOs research building and the microscope techniques already available in it with high resolution, thus closing a large existing gap.

一个现代的低温透射电子显微镜（低温TEM）的单粒子分析和低温层析成像应用。为了处理数据，计算集群是应用程序的一部分。cryo-TEM的收购是阿恩穆勒教授（主申请人）的新任命和结构生物学系的伴随建立的一部分。作为一个平台，这些设备将成为奥斯纳布吕克大学优秀基础设施的一部分，那里已经建立了必要的房间。在Möller小组中，该设备将用于确定膜蛋白的结构和功能，特别是与其脂质环境相关的结构和功能。这一重点也是奥斯纳布吕克大学的一个经典重点，这使我们期待该设备的密集跨学科使用。cryo-TEM将补充最近完成的CellNanOs研究大楼和其中已经提供的高分辨率显微镜技术，从而缩小现有的巨大差距。