A NEW FLEXOR TENDON REPAIR TECHNIQUE AND A ROLE OF ANGIOGENESIS UNDER POSTOPERATIVE MOBILIZATION

一种新的屈肌腱修复技术和术后松动中血管生成的作用

• 批准号: 10470307
• 负责人: KUBOTA Hideaki
• 金额: $ 4.42万
• 依托单位: KYUSHU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-10470307/
• 关键词: flexor tendon; active mobilization; epitenon; endotenon; absorbable suture; tendon repair; tendon healing; 自動連動療法; 吸収系; 腱治癒; entotenon

A new flexor tendon repair technique, that is the four-strand double modified locking Kessler core suture and the cross-stitch circumferential suture technique which was easy to perform yet adequate strength, was developed. We proved that this technique was mechanically superior to other similar suture techniques in cadaveric study.In vivo study, we evaluated this technique in healing tendons. Canine flexor tendon were repaired and evaluated following either active mobilization or immobilization. All tendons healed without rupture, thus demonstrating that this repair technique has enough tensile strength to withstand early active mobilization. Actively mobilized tendons healed without extrinsic adhesions nor large tendon calluses that were found in immobilized tendons.Furthermore, we evaluated the mechanical and histologic healing process of flexor tendon repair using absorbable suture thread followed by active mobilization. An inflammatory response was observed around the suture thread. However all tendons healed without initial tensile depression.In regard with suture loop configurations, we compared the effect of locking and grasping in four strand core suture techniques for tendon repair. The greatest tensile strength was found with the double modified locking Kessler technique which incorporated eight rectangular locking loop configurations.

开发了一种新的屈肌腱修复技术，即四股双改良锁定凯斯勒核心缝合技术和易于操作且强度足够的十字缝圆周缝合技术。我们在尸体研究中证明了该技术在机械上优于其他类似的缝合技术。在体内研究中，我们评估了该技术在肌腱愈合中的作用。在主动活动或固定后修复和评估犬屈肌腱。所有肌腱均愈合且未断裂，从而表明这种修复技术具有足够的抗拉强度，可以承受早期主动活动。主动活动的肌腱愈合时没有外在粘连，也没有固定肌腱中发现的大肌腱老茧。此外，我们评估了使用可吸收缝合线进行主动活动后屈肌腱修复的机械和组织学愈合过程。在缝合线周围观察到炎症反应。然而，所有肌腱均在没有初始拉伸凹陷的情况下愈合。关于缝合环配置，我们比较了四股芯缝合技术中锁定和抓握的效果。最大的拉伸强度是通过双重改进的锁定凯斯勒技术发现的，该技术结合了八个矩形锁定环配置。

项目成果

Kubota H, Wada A, Iwamoto Y, et.al.: "The results of surgical treatment of old Scaphoid fractures (Japanese)"The Journal of Japanese Society for Surgery of the Hand. 16(1). 82-84 (1999)

Kubota H、Wada A、Iwamoto Y等人：“陈旧性舟状骨骨折的手术治疗结果（日语）”日本手外科学会杂志。

Kubota H, Urabe K, Iwamoto Y: "Early active mobilization following Achilles tendon rupture repair With new suture technique"Orthopedics & Traumatology. 48(2). 461-464 (1999)

Kubota H、Urabe K、Iwamoto Y：“采用新缝合技术修复跟腱断裂后的早期主动活动”骨科

Wada A, Kubota H, Iwamoto Y, et.al.: "Mechanical properties of the 2-strand Tsuge core suture technique Using braided polyester thread (Japanese)"The Journal of Japanese Society for Surgery of the Hand. 17(3). 278-279 (2000)

Wada A、Kubota H、Iwamoto Y 等人：“使用聚酯编织线的 2 股 Tsuge 核心缝合技术的机械特性（日语）”日本手外科学会杂志。

和田晃房,窪田秀明 他: "吸収糸のポリディオキサノン糸を用いた窪田法による屈筋腱修復法の力学的強度"日本手の外科学会雑誌. 16・3. 402-404 (1999)

Akifusa Wada、Hideaki Kubota 等：“使用可吸收聚二氧环己酮线修复屈肌腱的 Kubota 方法的机械强度”日本手外科学会杂志 16・3（1999 年）。

Wada A, Kubota H, Iwamoto Y, et.al.: "The mechanical properties of locking and grasping suture loop configurations in four-strand core suture techniques"The Journal of Hand Surgery (British and European Volume). 25B(6). 548-551 (2000)

Wada A、Kubota H、Iwamoto Y 等人：“四股芯缝合技术中锁定和抓握缝合环结构的机械性能”《手外科杂志》（英国和欧洲卷）。