Study on health
Study on health
批准号:
10557200
负责人:
HARADA Nobuhiro
金额:
$6.59万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 2001
中文摘要
我们调查了口腔健康状况与健康促进因素之间的相关性。我们认为,口腔区域的健康促进因子将发挥重要作用,以防止一个人感染严重的疾病,通过呼吸和喂养。我们按照WHO口腔检查程序,对80岁时保留自己牙齿20颗的老年人(我们称之为8020人)进行了口腔检查。检测口腔细菌植物群组成、唾液成分、唾液容量、唾液缓冲能力。通过对血液成分、饮食习惯、运动能力等指标的研究,探讨其与口腔健康状况的关系。研究的细菌种为白色念珠菌、变形链球菌。远缘链球菌、肺炎链球菌、铜绿假单胞菌、金黄色葡萄球菌。此外,我们还对唾液中的抗菌肽,如防御素和组胺素进行了定量分析。
英文摘要
We investigated correlation between health status and health-promoting factors in the oral region. We assumed that health-promoting factors in the oral region would play an important role to prevent a man from infecting serious diseases through respiration and feeding. We performed oral examination of elderly people who keep their own teeth of 20 at the age of 80 (we call them 8020 people), according to WHO oral examination procedures. In detail, composition of oral bacterial flora, saliva constituent, saliva volume, salivary buffering were examined. Blood constituent, diet convention, athletic capacity were studied to clarify their relation with oral health status. Bacterial species studied were Candida albicans, Streptococcus mutans. Streptococcus sobrinus, Streptococcus pneumoniae, Psedomonos aeruginosa, Staphylococcus aureus. Haemophilias oarainfluenzae, etc. Furthermore, we put our attention on antibacterial peptide in saliva, such as defensin and histatin, and did quantitative analysis of these peptides.
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Murata, T.: "Periodontitis and serum interleukin-6 levels in the elderly"Jpn J Infect Dis. 54. 69-71 (2001)
Murata, T.:“老年人的牙周炎和血清白细胞介素 6 水平”Jpn J Infect Dis。
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ETO A: "Inhibitory effect of a self-derived peptide on glucosytransferase of Streptococcus mutans"J. Biol. Chem.. 274. 15797-15802 (1999)
ETO A:“自源肽对变形链球菌葡萄糖转移酶的抑制作用”J。
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Hanada N: "The relationship between oral health status and biological and psychosocial function 〜"Archirey of Gerontology and Geriatrics. 33. 133-140 (2001)
Hanada N:“口腔健康状况与生物和心理社会功能之间的关系〜”Archirey of Gerontology and Geriatrics 33. 133-140 (2001)
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Tada A, Hanada N, Tanzawa H.: "The relation between tube feeding and psendonouas aeruginous detection in the oval cavity"A. Biol. Sci. Med. Sci.. 57. 71-72 (2002)
Tada A,Hanada N,Tanzawa H.:“管饲与卵圆腔内假铜绿菌检测之间的关系”A。
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H.Takenchi: "New dental drug delivery system for removing mutans streptococci from the oral cavity."Jpn.J.Infect.Dis.. 53. 211-212 (2000)
H.Takenchi:“用于从口腔中去除变形链球菌的新型牙科药物输送系统。”Jpn.J.Infect.Dis.. 53. 211-212 (2000)
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共 57 条
Challenge to compact, intense, and repetitive light source by using liquid metal
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批准号:24656184
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2012
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负责人:HARADA Nobuhiro
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依托单位:
Epigenetic regulation of aromatase gene by changes of chromatin structure
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批准号:22591019
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.33万
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财政年份:2010
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负责人:HARADA Nobuhiro
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依托单位:
Metabolic regulation of estrogen-synthesizing enzymes by post-translational modification
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批准号:18591034
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.57万
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财政年份:2006
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负责人:HARADA Nobuhiro
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依托单位:
Study on the protection against estrogen-dependent cancer
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批准号:12213132
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$25.54万
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财政年份:2000
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负责人:HARADA Nobuhiro
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依托单位:
Experiments on High-Efficiency MHD Generation without Alkali Metal Seed
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批准号:11450109
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.34万
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财政年份:1999
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负责人:HARADA Nobuhiro
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依托单位:
Analysis of aromatase/estrogen system in the age-related diseases by developmental engineering techniques
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批准号:11470228
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:1999
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负责人:HARADA Nobuhiro
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依托单位:
Molecular mechanism of aberrant expression of estrogen synthetase in the age-related diseases
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批准号:09671080
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:1997
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负责人:HARADA Nobuhiro
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依托单位:
HIGH EFFICIENCY MHD POWER GENERATION WITHOUT USING ALKALIMETAL
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批准号:08455131
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.54万
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财政年份:1996
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负责人:HARADA Nobuhiro
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依托单位:
Analysis on the transcriptional regulation mechanism of aromatase gene
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批准号:02680163
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1990
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负责人:HARADA Nobuhiro
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依托单位:
海外基金