权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

ESTABLISHMENT OF FOOD HABITS HELPFUL TO PREVENT LIFE STYLE RELATED DISEASES BY USE OF ANTI-OXIDATIION AND ANTI-STRESS VITAMINS

建立饮食习惯，有助于通过使用抗氧化和抗应激维生素来预防与生活方式相关的疾病

基本信息

批准号：
10558006
负责人：
KURATA Tadao
金额：
$ 8.77万
依托单位：
OCHANOMIZU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B).
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 2000
项目状态：
已结题

项目摘要

Nowadays, prevention of various life style related disease is a great concern of most middle or higher aged Japanese people. Most Japanese people also know that food habits which actually control their nutrition and therefore their health is very important to reduce the risk to suffer from life style related diseases. On the other hand, diabetes, one of the most common and typical life style related diseases in Japan, is very popular in elderly people, and smoking is also known to increase the risk of lung cancer and give various effects on the development of these diseases including diabetes. L-ascorbic Acid, which is also called Vitamin C, is an essential water soluble nutrient, and is widely known to be involved in the bio-synthesis of collagen, metabolism of aromatic amino acids, lipid metabolism, activation of immune system and cell multiplication. Furthermore, owing to its strong electron donating property, Vitamin C is widely used as an antioxidant in various processed foods, and also very commonly believed to contribute to the improvement and promotion of our health by its anti-oxidation and anti stress function. In this study, we tried to clarify the details of the anti-oxidation function and anti-stress function of Vitamin C to make a proposal which will be helpful to establish the food habits to prevent various life style related diseases in the future. In short, we made various animal experiments and could obtain basic experimental data necessary to make our proposal, and also by the survey on the many reports on the biological, nutritional, anti-oxidative, anti-stress function of Vitamin C and its related compounds, we could get enough information to make our proposal for the establishment of food habits helpful to prevent life style related diseases by use of anti-oxidation and anti-stress vitamins.

如今，预防各种与生活方式有关的疾病是大多数日本中老年人群非常关注的问题。大多数日本人也知道饮食习惯实际上控制着他们的营养，因此他们的健康对于减少患生活方式相关疾病的风险非常重要。另一方面，糖尿病是日本最常见和典型的生活方式相关疾病之一，在老年人中非常流行，吸烟也会增加患肺癌的风险，并对包括糖尿病在内的这些疾病的发展产生各种影响。l -抗坏血酸又称维生素C，是人体必需的水溶性营养素，广泛参与生物合成胶原蛋白、芳香氨基酸代谢、脂质代谢、免疫系统激活和细胞增殖。此外，由于其强大的供电子特性，维生素C被广泛用作各种加工食品中的抗氧化剂，而且人们普遍认为它具有抗氧化和抗应激的功能，有助于改善和促进我们的健康。在本研究中，我们试图阐明维生素C的抗氧化功能和抗应激功能的细节，并提出建议，这将有助于在未来建立饮食习惯，预防各种生活方式相关疾病。总之，我们进行了各种动物实验，获得了提出建议所需的基本实验数据，并且通过对维生素C及其相关化合物的生物、营养、抗氧化、抗应激功能的许多报道的调查，我们可以获得足够的信息来提出我们的建议，建立有助于使用抗氧化和抗应激维生素预防生活方式相关疾病的饮食习惯。