Elucidation of membrane transport processes coupled with respiration mimetic reactions and development of novel membrane separation methods

点击翻译按钮获取中文摘要

Respiration mimetic membrane reactions were realized by adopting artificial membrane systems in the absence of any enzymes and proteins, in order to get a quantitative understanding of the energetics involved in the membrane transport in a living system as well as to develop novel biomimetic separation methods of ions. The fruits obtained are as follows.New Types of Membrane Reactions Mimicking biological ProcessesConsidering a membrane system such as aqueous (W1)/membrane (M)/aqueous (W2), the reaction that a charge is incorporated from W1 into M at one site of the W1|M interface and released from M to W1 at another site of the same interface can be regarded as a membrane transport ("Parallel transport I"). Another variety of "Parallel transport" is the reaction that a charge is released from M to W1 or W2 at one site of the W1|M or W2|M interface and incorporated from W1 or W2 to M at another site of the W1|M or W2|M interface. ("Parallel transport II"). These new transports were realized by using liquid membranes.Effect of a Phospholipid Adsorbed on the Aqueous/0rganic Interface on Ion Transfers at the InterfaceThe transfer of a hydrophilic cation such as alkali metal ion, alkaline earth metal ion or H^+ from an aqueous to an organic was found to be facilitated by the phospholipid layer. When the ion was hydrophobic cation or an anion, the facilitated transfer was not observed.Evaluation of Gibbs Energy for the Transfer of a Hydrophilic Ion from an Aqueous to an Organic SolutionA method to determine the transfer energy of a hydrophilic metal ion from an aqueous solution, W, in the presence of high concentration of H^+ to an organic solution, 0,.was proposed based on the theoretical consideration of the distribution process of ions between W and 0.