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The technological development of bioengineered regenerated tooth, based on the mechanism of development

The technological development of bioengineered regenerated tooth, based on the mechanism of development
基于发育机制的生物工程再生牙技术进展
批准号:
22249064
负责人:
KUBOKI Takuo
金额:
$29.87万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010-04-01 至 2014-03-31
关键词:

项目摘要

项目成果

KUBOKI Takuo的其他基金

相关文献

中文摘要
翻译
在牙科领域,完整牙齿的再生是最终目标。首先,我们研究了利用器官胚胎法从出生后的犬永久牙芽组织中能否再生全功能生物工程牙齿,这在世界上是第一次成功的。接下来,为了了解牙齿发育的机制,我们进行了筛选,明确了几个HOX基因在牙齿发育中特异表达。
英文摘要
In the dental field, the regeneration of complete tooth is ultimate goal. First, we examined whether fully functional bioengineered tooth could regenerate utilizing an organ germ method with the permanent tooth bud tissue of the post-natal canine, we succeeded in it, for the first time in the world. Next, in order to understand the mechanism of tooth development, we performed the screening and clarified that several Hox gene specifically expressed in the development of tooth.
期刊论文(37)
专著(0)
科研奖励(0)
会议论文
Expression Pattern of Hox Genes During Mouse Tooth Development
小鼠牙齿发育过程中Hox基因的表达模式
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Shinkawa S, Uchibe K, Ono M, Sonoyama W, Hara ES, Yoshioka Y, Ueda J, Asahara H, Kuboki T]
通讯作者: Kuboki T
抜歯窩肉芽組織からの新規間葉系幹細胞の同定
拔牙槽肉芽组织中新型间充质干细胞的鉴定
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [中島隆, 大野充昭, 園山亘, 笈田育尚, Emilio S.Hara, 前川賢治, 窪木拓男]
通讯作者: 窪木拓男
DOI: 10.1074/jbc.m112.343194
发表时间: 2012-04
期刊: The Journal of Biological Chemistry
影响因子: --
作者: [S. Yamashita;S. Miyaki;Y. Kato;Shigetoshi Yokoyama;Tempei Sato;F. Barrionuevo;H. Akiyama;G. Scherer;S. Takada;H. Asahara]
通讯作者: S. Yamashita;S. Miyaki;Y. Kato;Shigetoshi Yokoyama;Tempei Sato;F. Barrionuevo;H. Akiyama;G. Scherer;S. Takada;H. Asahara
DOI: 10.1007/s12079-012-0180-4
发表时间: 2013-03-01
期刊: JOURNAL OF CELL COMMUNICATION AND SIGNALING
影响因子: 4.1
作者: [El Kader, Tarek Abd, Kubota, Satoshi, Takigawa, Masaharu]
通讯作者: Takigawa, Masaharu
30
    Development of production technique of tissue derived stem cell using novel reprogramming system.
    • 批准号:
      25670818
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2013
    • 负责人:
      KUBOKI Takuo
    • 依托单位:
    Development of a technic to generate somatic stem cells using a newly reprogramming method.
    • 批准号:
      23659899
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2011
    • 负责人:
      KUBOKI Takuo
    • 依托单位:
    Establishment of Information Basis for Tooth Regeneration
    • 批准号:
      17209062
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $31.28万
    • 财政年份:
      2005
    • 负责人:
      KUBOKI Takuo
    • 依托单位:
    Establishment of a autologous cell transplantion method using mesenchymal stem cells for perio-dontal tissue and alveolus bone regeneration.
    • 批准号:
      14370632
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.47万
    • 财政年份:
      2002
    • 负责人:
      KUBOKI Takuo
    • 依托单位: