Acute and permanent monitoring of infectious patients using a contactless, multispectral, optical measuring system

使用非接触式多光谱光学测量系统对传染病患者进行急性和永久监测

• 批准号: 458611451
• 负责人: Professor Dr. Gunther Notni
• 金额: --
• 依托单位: Fachgebiet Elektronische Bauelemente und Schaltungen (EBS)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/458611451?language=en
• 关键词: Acute; permanent; monitoring; infectious; patients

The novel coronavirus SARS-CoV-2 was identified as the cause of a respiratory disease known as coronavirus disease (Covid-19). SARS-CoV-2 is transmitted by respiratory uptake of virus-containing aerosols or droplets from the exhaled air of virus carriers. Therefore, in addition to wearing a mouth-nose cover and maintaining a sufficient safety distance, avoiding unnecessary personal contact is one of the most important infection control strategies. After a stable phase in the course of the disease, patients suffering from COVID-19 can suffer from an increasing, life-threatening lack of oxygen saturation (SpO2) in the blood. If oxygen therapy fails, this can lead to necessary ventilator therapy or even the use of lung replacement procedures. However, bed capacities of intensive care and monitoring units are limited. In stable patients suffering from COVID-19, it is therefore important to closely monitor vital signs in order to detect a critical course as early as possible. Only this ensures an early transfer from the normal ward to an intensive care unit with initiation of the above mentioned actions under continuous monitoring. During lock-down, the regular check-ups of patients with chronic diseases were reduced in order to minimize the risk of infection. At the same time, those patients stated not to attend planned medical check-ups or even urgent medical consultations for fear of infection. The use of telemedical methods offers a high innovatory potential. Clinical studies have shown that telemedical management of patients with chronic diseases such as heart failure can be very successful in reducing mortality and hospital stays as well as improving quality of life and have been shown to be able to generate cost savings for the healthcare system. There is currently insufficient data for an evidence-based assessment of the benefit of telemedical applications in the context of an epidemic or pandemic. Even if there is a high technical innovation potential, care must be taken to ensure that these solutions are not developed without the users in mind. The aim of the project is to realize a miniaturized sensor system based on contactless determination of vital parameters (oxygen saturation, body temperature, respiratory rate, pulse). The development of a sensor system for the continuous, contactless monitoring of vital parameters would not only enable the early detection of a critical deterioration of initially stable COVID-19 patients, but could also lead to an optimized care of other patients with an increased risk of infection in the home based setting. Dynamic changes in vital parameters could indicate a worsening of health status. Early detection could prevent hospitalization by optimizing individual therapies. In case of a necessary hospitalization, personal contact and thus a possible transmission of infection from or to medical personnel could be minimized by contactless monitoring.

新型冠状病毒SARS-CoV-2被确定为一种名为冠状病毒病（Covid-19）的呼吸道疾病的病因。SARS-CoV-2通过从病毒携带者呼出的空气中吸入含病毒的气溶胶或飞沫传播。因此，除了佩戴口鼻罩和保持足够的安全距离外，避免不必要的个人接触是最重要的感染控制策略之一。在病程的一个稳定阶段之后，COVID-19患者可能会出现越来越严重的、危及生命的血液氧饱和度（SpO2）缺乏。如果氧气治疗失败，这可能导致必要的呼吸机治疗，甚至使用肺替代手术。但是，重症监护和监测单位的床位容量有限。因此，对于病情稳定的COVID-19患者，必须密切监测生命体征，以便尽早发现关键病程。只有这样才能确保及早从普通病房转到重症监护病房，并在持续监测下启动上述行动。在封锁期间，减少了对慢性病患者的定期检查，以最大限度地降低感染风险。与此同时，这些患者表示，由于担心感染，他们没有参加计划中的医疗检查，甚至没有参加紧急医疗咨询。远程医疗方法的使用具有很高的创新潜力。临床研究表明，对心力衰竭等慢性病患者进行远程医疗管理可以非常成功地降低死亡率和住院时间，并改善生活质量，并已证明能够为医疗保健系统节省成本。目前没有足够的数据来评估在流行病或大流行病背景下远程医疗应用的惠益。即使有很高的技术创新潜力，也必须注意确保在开发这些解决办法时不考虑到用户。该项目的目标是实现一个基于非接触式关键参数（血氧饱和度、体温、呼吸频率、脉搏）测定的小型化传感器系统。开发一种用于连续、非接触式监测重要参数的传感器系统，不仅可以早期发现最初稳定的COVID-19患者的严重恶化，还可以优化家庭环境中感染风险增加的其他患者的护理。生命参数的动态变化可能表明健康状况恶化。早期发现可以通过优化个体治疗来预防住院。在必要的住院治疗情况下，通过非接触监测可以最大限度地减少个人接触，从而最大限度地减少医务人员之间或向医务人员传播感染的可能。