Mechanisms of protection from SARS-CoV-2 by neutralizing and non-neutralizing monoclonal antibodies in a small animal model
Mechanisms of protection from SARS-CoV-2 by neutralizing and non-neutralizing monoclonal antibodies in a small animal model
批准号:
458682471
负责人:
Professor Dr. Klaus Überla
金额:
$0.0万
依托单位国家:
德国
项目类别:
Research Grants
财政年份:
2021
资助国家:
德国
项目状态:
已结题
起止时间:
2020-12-31 至 2021-12-31
中文摘要
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英文摘要
Neutralizing monoclonal antibodies to SARS-CoV2 have been shown to reduce viral load after challenge of passively immunized animals. Since the mechanisms of protection have not been defined the project aims to determine whether Fc-effector mechanisms contribute to protection and whether neutralizing and non-neutralizing antibodies to the SARS-COV-2 spike protein can prevent in vivo the infection of the first cells by viruses from the inocculum.
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依托单位:
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负责人:Professor Dr. Klaus Überla
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依托单位:
国内基金
海外基金
加密/签名的密钥泄露保护机制研究
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批准号:60970111
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项目类别:面上项目
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资助金额:33.0万元
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批准年份:2009
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负责人:陈克非
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依托单位: