Orthodontic diagnosis for cleft lip and palate patients based on analysis of scar tissue

基于疤痕组织分析的唇腭裂患者正畸诊断

• 批准号: 12470456
• 负责人: ISHIKAWA Hiroyuki
• 金额: $ 7.1万
• 依托单位: Fukuoka Dental College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-12470456/
• 关键词: Cleft lip and palate; Palatoplasty; Scar tissue; Laser Doppler flowmetry; Ultrasonic; Maxillary growth; Maxillary protraction; Orthodontic diagnosis; レーザードップラー; 口蓋粘膜; 血流計測; 超音波診断

This study was attempted to establish new orthodontic diagnosis for cleft lip and palate patients based on the analysis of post-surgical scar tissue. The non-contact laser Doppler flowmetry was applied to measure palatal tissue blood flow in order to analyze scar tissue distribution. This method is useful for analyzing the scar tissue distribution even in patients with severe palatal deformities. The ultrasonic device was applied to measure thickness of scar tissue formed across pterygoid-palatine junction. The effect of maxillary protraction was cephalometrically investigated in both unilateral cleft lip and palate and isolated cleft palate patients. The results suggested that forward displacement of the maxilla by treatment depends on individual growth potential of the maxilla influenced by the post-surgical tissue. Influence of palatal scar tissue on the maxillary anteroposterior growth was also investigated on rat's palates. The results suggest that anteroposterior growth inhibition is due to the suppression of bone addition by formed scar tissue across the transverse palatal suture.

这项研究试图根据手术后疤痕组织的分析来为唇裂和口感患者建立新的正畸诊断。使用非接触式激光多普勒流动仪进行测量pa骨组织血流，以分析疤痕组织分布。该方法对于分析严重pal骨畸形的患者即使是疤痕组织分布也很有用。将超声设备应用于测量跨翼状 - 五角星连接形成的疤痕组织的厚度。在单侧lip裂和pape和孤立的left裂患者中，对上颌突出的作用进行了齿状图。结果表明，通过处理对上颌骨的正向位移取决于受后术组织影响的上颌骨的个体生长潜力。还研究了大鼠味觉对pal骨疤痕组织对上颌前后生长的影响。结果表明，前后生长的抑制是由于横跨palatal缝线形成疤痕组织抑制骨骼的抑制作用。

项目成果

入江丈元, 他: "非接触式レーザードップラー血流計を用いた口蓋裂患者の口蓋形成術後瘢痕組織同定の試み"Orthodontic Waves. 62. 58-61 (2003)

Takemoto Irie 等人：“使用非接触式激光多普勒血流计识别腭裂患者腭成形术后的疤痕组织”Orthodontic Waves 62. 58-61 (2003)。

入江丈元, 他: "口蓋裂患者における上顎前方牽引装置の治療効果"日本口蓋裂学会雑誌. 26. 16-22 (2001)

Takemoto Irie 等人：“上颌前牙牵引装置对腭裂患者的治疗效果”，日本腭裂学会杂志 26. 16-22 (2001)。

Irie J, et al.: "The analysis of post-surgical scar tissue distribution on palates in cleft palate patients by non-contact Laser Doppler Flowmetry"Orthodontic Waves. 62(1). 56-61 (2003)

Irie J 等人：“通过非接触式激光多普勒血流测量法分析腭裂患者上颌术后疤痕组织的分布”正畸波。

金壮律, 他: "ラット口蓋部瘢痕組織が上顎骨の前後的成長に及ぼす影響"Orthodontic Waves. 60. 112-117 (2001)

Jong Ri Kim 等人：“大鼠腭部疤痕组织对上颌骨前后生长的影响”Orthodontic Waves。 60. 112-117 (2001)

入江丈元, 石川博之他: "口蓋裂患者における上顎前方牽引装置の治療効果"日本口蓋裂学会雑誌. 26・1. 16-22 (2001)

Takemoto Irie、Hiroyuki Ishikawa 等：“上颌前牙牵引装置对腭裂患者的治疗效果”日本腭裂学会杂志 26・1（2001 年）。