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Stabilization of cutaneous sensation elicited by electric stimulation and its application to sensory feedback

电刺激引起的皮肤感觉的稳定及其在感觉反馈中的应用

基本信息

批准号：
12558100
负责人：
FUTAMI Ryoko
金额：
$ 4.48万
依托单位：
Tohoku University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2002
项目状态：
已结题

项目摘要

The relationship between absolute threshold and the parameters of an electrical equivalent circuit for skin impedance was examined with neurologically intact subjects. The equivalent circuit consisted of resistance Rp and capacitance Cp connected in parallel, plus resistance Rs in series to both.As a result, for Ag-AgCl electrodes with electroconductive paste, variationsover time of the frequency characteristics of Rp and Cp were found to be similar to the changes caused by repeatedly stripping the skin. Values of Cp and Rp at 10Hz were found to relate to the absolute threshold with high correlation coefficients. Next we estimated the parameters of the equivalent circuit by measuring stimulus pulse current abd viltage waves of square-wave pulses using solid-gel electrodes. The absolute threshold increased with repeated electrical stimulation to the skin and decreased after adequate rest with no electrical stimulation. Rp decreased with repeated electrical stimulation and increased after rest, while Cp did not change. A significant correlation between Rp and the absolute threshold was observed. These results show that electrical stimulation to the stratum corneum affects both absolute threshold and skin impedance; they also indicate that real-time evaluation is important for stabilizing cutaneuos sensation elicited by electrical stimulation.Possible reasons for decreasing Rp were an increase of ionic conductivity due to osmosis of electroconductive paste into the stratum corneum due to charge transfer. The increase of the threshold amplitude was considered to be the result of broadened current pad due to increases if ionic or electric conductivities in the stratum corneum. It is necessary to clarify the mechanism of those relationsship between threshold and impedance parameters.

对神经功能正常的受试者进行了皮肤阻抗电学等效电路参数与绝对阈值之间的关系研究。等效电路由电阻Rp和电容Cp并联，加上串联的电阻Rs组成。结果表明，对于有导电浆料的Ag-AgCl电极，Rp和Cp的频率特性随时间的变化与反复剥离皮肤引起的变化相似。10赫兹的CP和Rp值与绝对阈值相关，相关系数很高。接下来，我们利用固体凝胶电极测量激励脉冲电流和方波脉冲的电压波来估计等效电路的参数。重复电刺激皮肤后，绝对阈值升高，充分休息而不电刺激后，绝对阈值降低。反复电刺激Rp降低，休息后Rp升高，而Cp无明显变化。Rp与绝对阈值之间存在显著的相关性。这些结果表明，电刺激角质层同时影响绝对阈值和皮肤阻抗；这也表明实时评估对于稳定电刺激引起的皮肤感觉是重要的。降低Rp的可能原因可能是由于电荷转移导致导电糊剂渗透到角质层而增加了离子电导率。阈值幅度的增加被认为是由于角质层的离子或电导增加而导致的电流垫加宽的结果。有必要弄清阈值与阻抗参数之间的关系的机理。