3 Tesla Magnetic Resonance Imaging Scanner (3T MRI Scanner)

这个新的3特斯拉核磁共振扫描仪的应用程序是位于<s:1>宾根大学诊所（UKT）山谷医学校园（“Klinikum Tal”）的精神健康校园（CMH）的一部分。CMH的目标是在精神卫生领域的所有部门之间建立临床和神经科学层面的紧密联系。新的CMH研究扫描仪将为山谷医学院（“Klinikum Tal”）的临床研究成像能力提供必要的扩展，而成像科学中心（ISC）将提供质量标准和安全法规。新的扫描仪将在结构上分配给精神科，并与放射科和ISC合作管理。在CMH安装新的MRI扫描仪的主要目标是：1)使CMH（医学院和UKT）以及邻近的临床心理学和生物心理学（理学院）的计划临床成像研究成为可能；ii)补偿现有的基于现有部门内部发展的新的扫描时间要求，iii)响应由于任命新教授（例如神经技术和计算精神病学，Tobias Kaufmann）而出现的扫描设备要求。因此，迫切需要在CMH及时建立一个研究专用的磁共振扫描设备。CMH研究环境的核心优势是集中了以核磁共振成像技术应用的不同方面为中心的大量专业知识，如社会认知（见中心倡议1:Birgit Derntl， Thomas eththofer, Benjamin Kreifelts, Marina Pavlova, Peter Dayan），脑刺激（见中心倡议2:Christian Plewnia， Surjo Soekadar, Alireza Gharabaghi, Ulf Ziemann/Christoph Zrenner），营养和大脑(见中心倡议3：Hubert Preissl, Jennifer Svaldi, Katrin Giel, Manfred Hallschmidt, Nils Kroemer)，发育障碍（见中心倡议4:Andreas fallgater， Ann-Christin Ehlis, Tobias Renner, Dirk Wildgruber），认知机制（见中心倡议5:Steffen Gais， Andreas Bartels, Axel Lindner, Karsten Rauss, Kou Murayama）和痴呆研究（见中心倡议6:Christoph Laske， Gerhard Eschweiler, Tobias Lindig）。这种物理集中将进一步使DFG资助的新的当地合作研究中心和多中心参与的大规模患者测量成为可能。本提案的申请人已成功申请参加9个bmbf资助的精神病学、心理治疗和心理学研究网络中的6个，提供必要的成像设备和合适的扫描仪是这些正在进行的和随后的长期成像计划的先决条件。

This application for a new 3 Tesla MRI scanner is part of the establishment of a Campus for Mental Health (CMH) located at the Valley Medical Campus (“Klinikum Tal”) of the University Clinic Tübingen (UKT). The aim of the CMH is to create tight interconnections both at clinical and neuroscientific level between all departments working in the field of mental health.The new CMH research scanner will provide the necessary expansion of clinical research imaging capacities at the Valley Medical Campus (“Klinikum Tal”), while quality standards and safety regulations will be provided by the Imaging Science Centre (ISC). The new scanner will be structurally assigned to the Department of Psychiatry and managed in cooperation with the Department of Radiology and the ISC. The major goals of the installation of a new MRI scanner at the CMH is to i) enable the planned clinical imaging research at the CMH (Medical Faculty and UKT) and the adjacent Departments of Clinical Psychology and Biological Psychology (Faculty of Sciences), ii) compensate for existing new scan time requirements based on internal development of existing departments and iii) respond to the requests for scanning facilities emerging due to appointment of new professors (e.g. Neurotechnology and Computational Psychiatry, Tobias Kaufmann). Thus, timely establishment of one research dedicated MR scanning facility at the CMH is strongly needed. A central strength of the CMH research environment is the concentration of a critical mass of MR-centered expertise on different aspects of application of MR imaging techniques, such as Social Cognition (see Center Initiative 1: Birgit Derntl, Thomas Ethofer, Benjamin Kreifelts, Marina Pavlova, Peter Dayan), Brain stimulation (see Center Initiative 2: Christian Plewnia, Surjo Soekadar, Alireza Gharabaghi, Ulf Ziemann/Christoph Zrenner), Nutrition and the Brain (see Center Initiative 3: Hubert Preissl, Jennifer Svaldi, Katrin Giel, Manfred Hallschmidt, Nils Kroemer), Developmental Disorders (see Center Initiative 4: Andreas Fallgatter, Ann-Christin Ehlis, Tobias Renner, Dirk Wildgruber), Mechanisms of Cognition (see Center Initiative 5: Steffen Gais, Andreas Bartels, Axel Lindner, Karsten Rauss, Kou Murayama) and dementia research (see Center Initiative 6: Christoph Laske, Gerhard Eschweiler, Tobias Lindig).This physical concentration shall further enable large-scale patient measurements for new local DFG funded collaborative research centers and multicenter participations. Applicants of this proposal have successfully applied to participate in 6 of 9 BMBF-funded research networks in psychiatry, psychotherapy and psychology and provision of necessary imaging facilities with suitable scanners is a prerequisite for these ongoing and the subsequent long term imaging initiatives.