Combined small-animal imaging device (PET/SPECT/CT)

组合式小动物成像设备（PET/SPECT/CT）

• 批准号: 460921835
• 金额: --
• 依托单位: Universität des Saarlandes
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/460921835?language=en
• 关键词: Combined; small; animal; imaging; device

A combined small-animal imaging scanner for positron emission tomography (PET) and single photon emission computed tomography is requested. Both imaging modalities allow the quantitative and qualitative three-dimensional visualization of disease-specific molecular processes on the molecular level in the living organism. No other imaging modality can provide this important information. PET/SPECT imaging allows the repetitive investigation of complex molecular processes, thus contributing to the understanding of several diseases such cancer, Alzheimer’s disease, cardio-vascular diseases, bone metabolism, etc. In combination with the computed tomography (CT), this molecular information can be correlated with anatomical datasets. Such imaging modalities are neither available at the Saarland University nor at the University Hospital. As can be seen from the application, there is a great interest of a broad spectrum of research groups for both imaging modalities. To strengthen the research location at Saarland University, the availability of a PET/SPECT imaging is therefore of great importance.A combined PET/SPECT system allows the application of the entire spectrum of all radionuclides, which is tremendous significance for the realization of envisaged research projects as the majority of projects require gamma- as well as positronemitter.

一个组合的小动物成像扫描仪正电子发射断层扫描（PET）和单光子发射计算机断层扫描的要求。这两种成像方式允许定量和定性三维可视化的疾病特异性分子过程的分子水平上的活生物体。没有其他成像方式可以提供这一重要信息。PET/SPECT成像允许重复调查复杂的分子过程，从而有助于了解几种疾病，如癌症，阿尔茨海默病，心血管疾病，骨代谢等，结合计算机断层扫描（CT），这种分子信息可以与解剖数据集。萨尔兰大学和大学医院都没有这种成像方式。从应用中可以看出，广泛的研究小组对这两种成像方式都有很大的兴趣。为了加强萨尔兰大学的研究位置，PET/SPECT成像的可用性因此非常重要。组合PET/SPECT系统允许应用所有放射性核素的整个光谱，这对于实现设想的研究项目具有巨大的意义，因为大多数项目需要伽马以及正电子发射体。