权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Detection of environmental pollutants and study of natural hormones using compact, robust, high-power terahertz (THz) radiation source

使用紧凑、坚固、高功率太赫兹 (THz) 辐射源检测环境污染物并研究天然激素

基本信息

批准号：
13555015
负责人：
SARUKURA Nobuhiko
金额：
$ 8.45万
依托单位：
Institute for Molecular Science (2004)Okazaki National Research Institutes (2001-2003)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2004
项目状态：
已结题

项目摘要

Recently, chemical substances that have been artificially developed, particularly hormones that affect man's daily life as an endocrine disrupting substance have been ascertained to cause big environmental problems. These chemicals that mimics natural hormones are environmental concerns of global scale proportions, thus the detection of these environmental pollutants requires immediate attention and action. In addition to the existing environmental pollution monitoring devices, simple and highly sensitivity measurement technique is of vital importance. As such, we developed a system that detects and identifies endocrine disrupting substances using terahertz (THz) electromagnetic wave. An InAs semiconductor wafer was used in generating THz radiation and we succeeded in the enhancing the power of such radiation by applying a magnetic field from a novel and compact magnetic circuit consisting of eight permanent magnets. In this system, the InAs was excited using a portable (A4-size) and u … More ltrashort pulse mode synchronous fiber laser with a turn-key feature. Furthermore, we successfully developed a waveguide designed to operate in the THz frequency region. Until recently, strongly-polarization preserving and flexible THz waveguides have not been realized. We were able to overcome this obstacle problem by fabricating Teflon-based photonic crystal fiber waveguide whose transmissivity was found to be relatively high in the THz regime. In the previous year, the feasibility of THz absorption spectroscopy in the identification of hydroxy-substituted naphthalene (naphthol) isomers was demonstrated. The importance of such work was due to the fact that long-term exposure to naphthol, a biochemical that exhibits estrogenic like activity and is potentially mimic natural hormones, can cause liver problems. Using a similar experimental setup for this year, temperature-dependent transmission spectroscopy of a dihydroxy-substituted naphthalene, particularly the 1,4-naphthol, was utilized to observe the onset of its solid-state phase transition. An abrupt emergence of two distinct absorption peaks in the THz spectrum at 210K manifested evidence of an impending phase transition. The actual transition was verified by differential scanning calorimetry (DSC) analysis and temperature dependent x-ray diffractometry (XRD) measurements and was found to occur at 240K. Less

近年来，人工开发的化学物质，特别是作为内分泌干扰物质影响人类日常生活的激素，已被确定会引起大的环境问题。这些模拟天然激素的化学物质是全球规模的环境问题，因此检测这些环境污染物需要立即关注和采取行动。除了现有的环境污染监测设备外，简单、高灵敏度的测量技术至关重要。因此，我们开发了一种使用太赫兹（THz）电磁波检测和识别内分泌干扰物质的系统。InAs半导体晶片被用于产生THz辐射，我们成功地通过从由八个永磁体组成的新颖而紧凑的磁路施加磁场来增强这种辐射的功率。在该系统中，使用便携式（A4大小）和使用的InAs激发 ...更多信息具有交钥匙功能的超短脉冲模式同步光纤激光器。此外，我们成功地开发了一种波导设计工作在太赫兹频率范围。直到最近，强偏振保持和柔性太赫兹波导尚未实现。我们能够克服这一障碍的问题，通过制作聚四氟乙烯基光子晶体光纤波导的transmands被发现是相对较高的太赫兹制度。在过去的一年中，太赫兹吸收光谱在鉴定羟基取代的萘（萘酚）异构体的可行性得到了证明。这项工作的重要性是由于长期暴露于萘酚，一种表现出雌激素样活性的生化物质，可能会引起肝脏问题。使用今年类似的实验装置，利用二羟基取代萘，特别是1，4-萘酚的温度依赖性透射光谱来观察其固态相变的开始。在210 K的太赫兹光谱中突然出现两个明显的吸收峰，表明相变即将发生。通过差示扫描量热法（DSC）分析和随温度变化的X射线衍射法（XRD）测量验证了实际的转变，并发现发生在240 K。少