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Development of a Phacoemulsifier with an Intracameral Pressure Control Function

具有前房压力控制功能的超声乳化器的研制

基本信息

批准号：
13555119
负责人：
ARAKI Mituhiko
金额：
$ 3.9万
依托单位：
KYOTO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2002
项目状态：
已结题

项目摘要

Safe phacoemulsification requires stable anterior chamber. In this research, we have developed an intracameral pressure controller for a phacoemulsifier. To be concrete, 1) two control methods of the intracameral pressure, constant regulation method, which is to maintain the intracameral pressure at a constant level, and differential regulation method, which is to suppress the rate of change of the intracameral pressure, were proposed and evaluated by experiments, 2) an estimation method of the intracameral pressure was studied, and 3) an actuator for the intracameral pressure control was developed and evaluated by experiments. The obtained results are as follows.・ Both control methods have enough performance of intracameral pressure control, and the differential regulation method is more appropriate from the viewpoint of the safety and the possibility of implementation.・ By comparing the pressures at the infusion side and at the suction side with that in the anterior chamber, it is confirmed that the change of the pressure at the infusion side is highly similar to the change of the pressure in the anterior chamber. From this result, we can use the pressure at the infusion side for intracameral pressure control.・ An actuator for the differential regulation of the intracameral pressure, which is small enough for a phacoemulsifier, was developed, and it was confirmed that it has enough performance of intracameral pressure control by experiments.As mentioned above, the developed controller has enough performance of intracameral pressure control and safety for clinical application. It will contribute to improvement in safety of phacoemulsification-aspiration surgery.

安全的超声乳化术需要稳定的前房。在这项研究中，我们已经开发了一种用于超声乳化器的前房内压力控制器。具体而言，1）提出并通过实验评价了两种前房内压控制方法，即将前房内压保持在恒定水平的恒定调节方法和抑制前房内压变化率的差分调节方法，2）研究了前房内压的估计方法，3）研制了一种用于前房压力控制的致动器，并进行了实验评价。得到的结果如下。·两种控制方法都具有足够的前房压力控制性能，从安全性和实施的可能性角度考虑，差动调节方法更合适。通过将注入侧和吸引侧的压力与前房中的压力进行比较，确认注入侧的压力变化与前房中的压力变化高度相似。根据该结果，我们可以使用输注侧的压力进行前房内压力控制。·研制了一种用于超声乳化手术的前房压差调节致动器，并通过实验验证了该致动器具有足够的前房压差控制性能，说明所研制的控制器具有足够的前房压差控制性能和安全性，可用于临床。这将有助于提高白内障超声乳化吸除术的安全性。