Research on the Thermo-sensitive Phase Separable Solutions and Their Applications for Solution-phase Organic Reactions and Separations
Research on the Thermo-sensitive Phase Separable Solutions and Their Applications for Solution-phase Organic Reactions and Separations
批准号:
15350053
负责人:
CHIBA Kazuhiro
金额:
$8.19万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2003
资助国家:
日本
项目状态:
已结题
起止时间:
2003 至 2004
中文摘要
介绍了一种新的热态有机溶液体系,以实现多种液相组合化学。结果表明,由环烷烃组成的有机溶液与典型的极性有机溶剂在室温下可形成相分离的均相溶液。在这种情况下,环烷烃有效地进行了热敏相变。环烷烃相分离体系广泛应用于多种液相组合化学中。
英文摘要
A new thermomorphic organic solution system was introduced to accomplish wide variety of liquid-phase combinatorial chemistry. It was found that the combination of organic solutions composed of cycloalkanes and typical polar organic solvents formed phase-separable homogeneous solutions at ambient temperature. In this case, cycloalkanes effectively worked for the thermally sensitive phase-transformation. The cycloalkane phase separable systems were widely applied for several kind of liquid-phase combinatorial chemistry.
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Calcineurin inhibitors block dorsal-side signaling that affects late-stage development of the hearte during Xenopus embryogenesis
钙调神经磷酸酶抑制剂阻断影响非洲爪蟾胚胎发生过程中心脏后期发育的背侧信号传导
DOI:
--
发表时间:
2004
期刊:
Development Growth & Differentiation 46
影响因子:
--
作者:
[Yinggung Wu, M.Tabata, Yoko Yoshida]
通讯作者:
Yoko Yoshida
DOI:
--
发表时间:
2005
期刊:
Peptide Science (印刷中)
影响因子:
--
作者:
[I.-W.Hwang, T.K.Ahn, D.M.Ko, D.Kim, T.Kamada, T.Nakamura, A.Tsuda, A.Osuka, Kazuhiro Chiba]
通讯作者:
Kazuhiro Chiba
Yoko Yoshida, Shokaku Kim, Kazuhiro Chiba, Shinya Kawai, Hiroyuki Tachikawa, Nobuhiro Takahashi: "Calcineurin inhibitors block dorsal-side signaling that affects late-stage development of the heart, kidney, liver, gut, and somitic tissue during Xenopus em
Yoko Yoshida、Shokaku Kim、Kazuhiro Chiba、Shinya Kawai、Hiroyuki Tachikawa、Nobuhiro Takahashi:“钙调神经磷酸酶抑制剂阻断背侧信号传导,影响非洲爪蟾发育过程中心脏、肾脏、肝脏、肠道和体细胞组织的后期发育。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Synthesis and anti-barnacle activities of novel 3-isocyanotheonellin analogues
新型3-异氰酸酯类似物的合成及其抗藤壶活性
DOI:
--
发表时间:
2004
期刊:
Biofouling 20
影响因子:
--
作者:
[M.Goto, K.Otsuka, X.Chen, Y.Tao, M.Oyama, Kitano Yoshikazu]
通讯作者:
Kitano Yoshikazu
Calcineurin inhibitors block dorsal-side signaling that affects late-stage development of the heart, kidney, liver, gut, and somitic tissue during Xenopus embryogenesis
钙调神经磷酸酶抑制剂阻断背侧信号传导,影响非洲爪蟾胚胎发生过程中心脏、肾脏、肝脏、肠道和体细胞组织的后期发育
DOI:
--
发表时间:
2004
期刊:
Development Growth & Differentiation 46
影响因子:
--
作者:
[Yoko Yoshida, Shokaku Kim, Kazuhiro Chiba, Shinya Kawai, Hiroyuki Tachikawa, Nobuhiro Takahashi]
通讯作者:
Nobuhiro Takahashi
共 9 条
Solution-Phase Chemical Synthesis of Insulin by using Reverse-Micellar Continuous Reaction Method
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批准号:24380061
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.65万
-
财政年份:2012
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负责人:CHIBA Kazuhiro
-
依托单位:
Basic research on mechanism of lumbar disc degeneration and ne w development of treatment
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批准号:22591642
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2010
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负责人:CHIBA Kazuhiro
-
依托单位:
Large-scale syntheses of multi-bridged peptides that require complicated synthetic processes
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批准号:21380072
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.23万
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财政年份:2009
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负责人:CHIBA Kazuhiro
-
依托单位:
Link between estrogen and TGF-beta signaling in intervertebral disc metabolism - possible therapeutic target for degenerative disc disease
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批准号:19591734
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:CHIBA Kazuhiro
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依托单位:
Development of Exhaustive Synthesis of Glycopeptides by using Multiphase Organic Reaction System
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批准号:18380071
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.72万
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财政年份:2006
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负责人:CHIBA Kazuhiro
-
依托单位:
Molecular and cellular approaches to the treatment of degenerative lumbar disc disease
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批准号:17591595
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
-
财政年份:2005
-
负责人:CHIBA Kazuhiro
-
依托单位:
The basic research of the mechanism and the treatment for intervertebral disc degeneration.
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批准号:15591601
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2003
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负责人:CHIBA Kazuhiro
-
依托单位:
Development of a novel tissue culture system for the intervertebral disc
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批准号:13671540
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2001
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负责人:CHIBA Kazuhiro
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依托单位:
Systematic Synthesis of Bioactive Compounds Using Photochemical Method
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批准号:12650846
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2000
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负责人:CHIBA Kazuhiro
-
依托单位:
Effect of various cytokines on the metabolism of intervertebral disc cells cultured in vitro
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批准号:10671382
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:1998
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负责人:CHIBA Kazuhiro
-
依托单位:
海外基金