Evaluation and dissemination of evidence-based health information about the effectiveness of exercise and physical activity

评估和传播有关锻炼和体育活动有效性的循证健康信息

• 批准号: 15500476
• 负责人: OHSAWA Isao
• 金额: $ 1.34万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15500476/
• 关键词: exercise; physical activity; diabetes mellitus; hypertension; malignant neoplasm; cancer; clinical epidemiology; EBM

Through MEDLINE searches, we retrieved and reviewed English-language articles about the effectiveness of exercise and physical activity on diabetes mellitus, hypertension and malignant neoplasm.1.Diabetes mellitus (randomized controlled trials between 1985 and 2003)Three mega trials revealed that active life style reduced the incidence of type 2 diabetes. Fourteen out of 23 articles reported that HbAlc levels were significantly decreased in exercise group compared to control group.2.Hypertension (randomized controlled trials between 2000 and 2004)There were 12 articles that showed the beneficial effect of exercise on blood pressure among 21 articles. But the effects of exercise were weaker than those of diuretics and dietary sodium reduction.3.Malignant neoplasm (prospective cohort studies between 2000 and 2004)Four out of 7 articles showed that those who were physically active had lower cancer mortality. Inverse relationships were observed between active life style and risks for breast, colorectal, endometrial, and pancreatic cancers. The results were inconsistent about the associations of physical activity with risks of prostate, ovarian, renal cell, and bladder cancers.

通过MEDLINE检索，我们检索并回顾了关于运动和体力活动对糖尿病、高血压和恶性肿瘤的有效性的英文文章。1.糖尿病（1985年至2003年的随机对照试验）三项大型试验表明，积极的生活方式降低了2型糖尿病的发病率。23篇文献中有14篇报道运动组HbAlc水平较对照组显著降低。2.高血压（2000 - 2004年随机对照试验）21篇文献中有12篇显示运动对血压有益。3.恶性肿瘤（2000 - 2004年前瞻性队列研究）7篇文献中有4篇表明，经常锻炼的人癌症死亡率较低。积极的生活方式与乳腺癌、结直肠癌、子宫内膜癌和胰腺癌的风险呈负相关。结果是不一致的身体活动与前列腺癌，卵巢癌，肾细胞癌和膀胱癌的风险。