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An a amination of as rent of blood vessel stiffness by power spectral analysis of blood vessel sounds.

通过血管声音的功率谱分析对血管硬度进行胺化。

基本信息

批准号：
15500486
负责人：
OBARA Shigeru
金额：
$ 0.7万
依托单位：
The University of Tokushima
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2004
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15500486/
关键词：
blood vessel stiffness blood vessel sounds power spectral analysis exercise stress test 血管硬化度周波数解析

项目摘要

We can catch blood vessel sounds by a stethoscope at the time of the blood pressure measurement This sound occurs because of turbulence of bloodstream in a blood vessel. We hypothesized that there might be a difference in peak frequency (PHz as follows) of blood vessel sounds by power spectral analysis according with a condition of blood vessel wall, e.g. vessel stiffness. To determine this hypothesis, we performed an experiment about 17 persons whose age were 19-63 years old as subjects. Blood vessel sounds frequency was measured at rest, and during cycle ergometer exercise at light load (20-30 w), mild load (50-60 w), and middle load (90-120 w). The PHzs of three young subjects were less than 100Hz, and one young subject was around 150Hz at rest condition. However, one subject (49 yr) showed low PHz of 93.8 Hz, and another 12 middle-aged subjects showed higher PHz that were 100-170 Hz. Among middle-aged persons, regularly exercised persons showed lower PHz than that of non- regularly exercised persons. The PHz increased by exercise with most people, but individual difference was seen in a pattern of increase. The subjects who had higher values of PHz at rest showed a tendency of higher PHz in exercise, too. For example, a subject who's PHz at rest was about 150Hz showed the value of PHz of about 250Hz, while PHzs of another subjects were 110-230 Hz. The PHzs of 4 young subjects were 110-170 Hz. There is the remainder to examine in detail about this hypothesis, these results suggested that the value of PHz by power spectral analysis may imply blood vessel stiffness at rest, and the value of PHz during exercise may amplify the difference of blood vessel condition.

测量血压时，我们可以用听诊器捕捉到血管的声音。这种声音是由于血管内的血流紊流而产生的。我们通过功率谱分析推测，根据血管壁的状况，例如，血管声音的峰值频率（如下PHZ）可能存在差异。血管刚度。为了证实这一假设，我们对 17 名年龄在 19-63 岁之间的人进行了实验。在休息时以及轻负荷（20-30瓦）、轻度负荷（50-60瓦）和中负荷（90-120瓦）的自行车测功机运动期间测量血管声音频率。三名年轻受试者的 PHz 低于 100Hz，一名年轻受试者在休息状态下的 PHz 约为 150Hz。然而，一名受试者（49 岁）显示出 93.8 Hz 的低 PHz，另外 12 名中年受试者显示出较高的 PHz，为 100-170 Hz。在中年人中，经常锻炼的人的 PHz 低于不经常锻炼的人。大多数人的 PHz 会因运动而增加，但增加的模式存在个体差异。静息时 PHz 值较高的受试者在运动时也表现出较高 PHz 值的趋势。例如，静止时 PHz 约为 150Hz 的受试者显示的 PHz 值为约 250Hz，而另一受试者的 PHz 为 110-230Hz。 4 名年轻受试者的 PHz 为 110-170 Hz。关于这一假设还有待详细检验，这些结果表明功率谱分析的 PHz 值可能暗示静息时的血管硬度，而运动时的 PHz 值可能会放大血管状况的差异。