Interaction between cholesterol-bearing amphiphilic polyelectrolytes and surfactants

带有小摩尔百分比（5摩尔%）的胆固醇基部分的疏水改性的聚磺酸盐在水中形成分子间桥连的花胶束，其由聚合物结合的胆固醇基的分子间缔合产生。利用^1H NMR自旋-自旋弛豫时间、静态光散射、准弹性光散射和荧光技术研究了胆酸钠（SC）与该聚合物胶束在水中的结合。的聚合物结合的胆固醇基团的分子间关联被破坏，在一定程度上，通过添加SC，导致在形成的复合物的聚合物结合的胆固醇基团和SC。为了研究聚合物结合的胆固醇基团和SC之间的相互作用，胆固醇基团标记与萘部分。萘标记物的荧光光谱和NMR自旋-自旋弛豫时间数据表明，聚合物结合的胆固醇基团和SC的聚集体之间的相互作用发生在低于SC在水中的临界胶束浓度。

A hydrophobically modified polysulfonate bearing a small mole percent (5 mol %) of cholesteryl moieties forms an intermolecularly bridged flower micelle in water, arising from intermolecular associations of the polymer-bound cholesteryl groups. Binding of sodium cholate (SC) to this polymer micelle in water was investigated using ^1H NMR spin-spin relaxation time, static light scattering, quasi-elastic light scattering, and fluorescence techniques. The intermolecular association of the polymer-bound cholesteryl groups was disrupted, to some extent, by the addition of SC, resulting in the formation of complexes of the polymer-bound cholesteryl groups and SC. To investigate interactions between the polymer-bound cholesteryl groups and SC, the cholesteryl groups were labeled with a naphthalene moiety. Fluorescence spectra of the naphthalene labels and NMR spin-spin relaxation time data suggested that interactions between the aggregates of the polymer-bound cholesteryl groups and SC occurred below a critical micelle concentration of SC in water.