MRI analyses of brain lesion in canine distemper encephalitis

犬瘟热脑炎脑部病变的MRI分析

• 批准号: 15580287
• 负责人: MATSUNAGA Satoru
• 金额: $ 2.05万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15580287/
• 关键词: MRI; Canine distemper virus; encephalitis; Dog

The Theme of this research was MRI analyses of brain lesion in canine distemper encephalitis. In the acute phase of canine distemper encephalitis, there were no changes in the brain ; inflammatory effects and ventricular enlargement. These results revealed that MRI is not diagnostic tool in the acute phase of canine distemper encephalitis.On the other hand, in some phase of canine distemper encephalitis, there were changes that narrow brain ditch, enlargement of lateral and third ventricles and rounding of lateral ventricles. This phase may show heavy inflammation time.And, in the phase that there were no inflammation in brain parenchyma and no rounding in lateral ventricles, the brain ditches were enlarged. This findings may show the chronic period of the canine distemper encephalitis.Finally, in this study, the antibody test and the antigen test of canine distemper virus were not useful in the diagnosis of canine distemper encephalitis.

本研究的主题是犬瘟热脑炎脑病变的MRI分析。在犬瘟热脑炎的急性期，大脑没有变化;炎症反应和脑室扩大。结果表明，MRI对犬瘟热脑炎急性期的诊断价值不大，但在犬瘟热脑炎的某些阶段，可出现脑沟变窄、侧脑室和第三脑室扩大、侧脑室变圆等改变。在脑实质无炎症、侧脑室无变圆的阶段，脑沟扩大。最后，犬瘟热病毒的抗体检测和抗原检测在犬瘟热脑炎的诊断中并不具有实用价值。